Forty infants, 6 to 36 mo old, with iron-deficiency anemia (hemoglobin < 11 g/dL) were matched and assigned to two groups. One group received FeS0(4) and the other received ferrous bis-glycinate chelate at a dose of 5 mg of Fe daily per kilogram of body weight for 28 d. Both groups had significant hemoglobin increases (P < 0.001), but only the group treated with ferrous bis-glycinate chelate ha...

Abstract Observations of high ferric iron content in diamond garnet inclusions and mantle plume melts suggest a highly heterogeneous distribution the mantle. Recycling oxidized materials such as carbonates from Earth’s surface by subduction could explain observed variations. Here we present high-pressure high-temperature multi-anvil experiments to determine redox reactions between calcium-, mag...

A variety of acidophilic microorganisms were shown to be capable of oxidizing formate. These included Thiobacillus ferrooxidans ATCC 21834, which, however, could not grow on formate in normal batch cultures. However, the organism could be grown on formate when the substrate supply was growth limiting, e.g., in formate-limited chemostat cultures. The cell densities achieved by the use of the lat...

[1] Galileo spacecraft data obtained from Jupiter’s ice-covered satellite Europa suggest the existence of a subsurface water ocean. The formation of this ocean is a direct consequence of early igneous and hydrothermal processes that may have facilitated oxidation through H2 and CH4 escape. These processes could have led to a moderately alkaline sulfate-carbonate ocean and a moderately oxidized ...

Friedreich's ataxia is associated with a deficiency in frataxin, a conserved mitochondrial protein of unknown function. Here, we investigate the iron binding and oxidation chemistry of Escherichia coli frataxin (CyaY), a homologue of human frataxin, with the aim of better understanding the functional properties of this protein. Anaerobic isothermal titration calorimetry (ITC) demonstrates that ...

INTRODUCTION In an oral iron absorption test (OIAT), the rise in plasma iron concentration after oral ingestion of iron is a measure of intestinal iron absorption. We describe results of the OIAT using two different formulations of oral iron drops. METHODS The study included all patients who had an OIAT performed at the Department of Internal Medicine, Farsø, Aalborg University Hospital, Denm...

A rapid technique for the determination of iron in serum, after the intravenous injection of iron-dextran, is presented. Dithionite is used for the reduction of ferric to ferrous iron. The use of a detergent solution enables protein precipitation to be omitted. The iron reagent, 4: 7-diphenyl-1: 10-phenanthroline, and its ferrous complex are both soluble in the dilute detergent solution. Lipaem...

Profundal sediments of Lake Constance were sampled at 60 130 m water depth and studied with respect to the population sizes and depth distribution of mixotrophic and lithotrophic iron oxidizing, denitrifying bacteria. The sediment cores showed a distinct stratification with oxygen and nitrate being consumed within the first centimeter of the sediment. The sediment contained large amounts of aci...

Six Gardnerella vaginalis strains were examined for the ability to utilize various iron-containing compounds as iron sources. In a plate bioassay, all six strains acquired iron from ferrous chloride, ferric chloride, ferrous sulfate, ferric ammonium citrate, ferrous ammonium sulfate, bovine and equine hemin, bovine catalase, and equine, bovine, rabbit, and human hemoglobin. All six strains also...

background and objectives: in the original in vitro method for evaluation of iron bioavailability using caco-2 cell model, ferritin formation by cells is considered as a functional indicator of both absorption and utilization of iron. however, as iron is measured in the tested material and then ferritin concentration is measured in caco-2 cell lysate, it is almost impossible to have a concrete ...