The effects of pancreatic hormones and cyclic AMP on the induction of ketogenesis and long-chain fatty acid oxidation were studied in primary cultures of hepatocytes from fetal and newborn rabbits. Hepatocytes were cultivated during 4 days in the presence of glucagon (106 M), forskolin (2 x 10'M), dibutyryl cyclic AMP (10-' M), 8-bromo cyclic AMP (10-' M) or insulin (10-' M). Ketogenesis and fa...

the umbilical vein (uv) has a non pulsating and even pattern in normal fetuses. pulsation of uv has been described in severely growth restricted fetuses with chronic hypoxia. we wanted to see whether uv pulsations could also be seen in fetuses with heart deceleration during labor, as an adjunctive measure to assess the intra partum hypoxia. in a prospective study doppler examination was perform...

mother's mental health status during pregnancy has important effects on fetal growth and development. however, there are few studies concerning association of maternal depression and biophysical profile (bpp) of the fetus. we performed this research to know if maternal depression has any association with fetal bpp score. for measuring depression, farsi version of patient health questionnaire-9 ...

Mitophagy is one of the selective autophagy pathways that catabolizes dysfunctional or superfluous mitochondria. Under mitophagy-inducing conditions, mitochondria are labeled with specific molecular landmarks recruit machinery to surface mitochondria, enclosed into autophagosomes, and delivered lysosomes (vacuoles in yeast) for degradation. As damaged major sources reactive oxygen species, mito...

By the use of ultrasound, chemical analysis and histologic techniques, the knowledge of embryo and fetal growth and developments is increasing steadily.  It has been demonstrated that the fetus can respond to sound, bright light and touch. Accordingly, works on fetal responses to external stimuli during the third trimester may ultimately lead to improve­ments in the techniques of antepartum fe...

extract  in this study, position of fetus were examined in the different weeks of pregnancy and their association with fetus presentation in during labor. the study group included women who had normal condition. the aim of this study include:   1- to determine the distribution normal position of fetus before birth.   2- to determine the possibility of concurrent position of fetus in during preg...

acrolein (acr) is α, β unsaturated aldehyde that exists extensively in the environment and (thermally processed) foods. it can also be generated through endogenous metabolism. the aim of this study was to investigate the possible protective role of pentoxifylline (ptx) is a non-selective phosphodiesterase (pde) inhibitor on toxicity of acr. in this study, oxidative damage were measured by marke...

conclusions in conclusion, at measurement can be beneficial for the safety or recovery of malathion-induced toxic injury in liver tissue and liver mitochondria. results in liver tissue, the activity of lpo and cat was higher in the malathion group in comparison to controls. at reduced malathion-induced lpo, sod, cat, and gpx in rat liver. coadministration of at with malathion improved lpo, sod,...

Epidemiologic data suggest a strong association between low birth weight and increased risk of metabolic syndrome in adult life. However, the underlying mechanisms are largely unknown. To test the hypothesis that mitochondrial changes may serve as a link between poor nutrition in early life and insulin resistance in later life, we investigated the effect of protein malnutrition during gestation...