Colorectal cancer (CRC) is one of the most common malignant neoplasms worldwide. Except for the existing fecal occult blood test, colonoscopy and sigmoidoscopy, no widely accepted in vitro diagnostic methods have been available. To identify potential peptide biomarkers for CRC, serum samples from a discovery cohort (100 CRC patients and 100 healthy controls) and an independent validation cohort...

-The phenotypic forking GA (p-fGA) which divides the whole search space into sub-spaces using the information of the convergence status of the population and the solutions obtained so far had already been developed. In that work, a neighborhood hypercube was defined around the best individual at the time of forking in the phenotypic feature space with the best solution as the center of that hyp...

Allele and genotype frequencies for 15 short tandem repeat (STR) polymorphisms--D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX and FGA--in a Japanese population were estimated. No deviations of the observed allele frequency from Hardy-Weinberg equilibrium expectations were found for any of the systems studied. Between 2 new pentanuc...

ABSTRACT Introduction Mild traumatic brain injury (mTBI) is associated with significant financial cost and reduced military readiness impacts quality of life for active duty service members (SMs). Post-concussive symptoms can include vestibular impairments, such as chronic dizziness postural instability, which be compounded by psychological comorbidities like PTSD. Comprehensive evaluations are...

We fabricated Al/Al 2 O xmlns:xlink="http://www.w3.org/1999/xlink">3 /SiO /Si and Al/HfO structures to optimize the passivation layer of a backside-illuminated (BSI) complementary metal oxide semiconductor (CMOS) image sensor (CIS), with key properties newly developed high- <inline-formula...

User counterparts, such as user attributes in social networks or interests, are the keys to more natural Human–Computer Interaction (HCI). In addition, users’ and structures help us understand complex interactions HCI. Most previous studies have been based on supervised learning improve performance of However, real world, owing signal malfunctions devices, large amounts abnormal information, un...

PURPOSE Bladder carcinogenesis is believed to follow alternative pathways of disease progression driven by an accumulation of genetic alterations. The purpose of this study was to evaluate associations between measures of genomic instability and bladder cancer clinical phenotype. EXPERIMENTAL DESIGN Genome-wide copy number profiles were obtained for 98 bladder tumors of diverse stages (29 pT(...