Bacterial resistance has become an important challenge in the treatment of urinary tract infections. The underlying mechanisms can most likely be circumvented with antiadhesive approach, antagonizing lectin FimH located at tip fimbriae uropathogenic E. coli. Here we report on a novel series antagonists based 1-(?-d-mannopyranosyl)-4-phenyl-1,2,3-triazole scaffold, designed to incorporate carbox...

Background: Urinary tract infections (UTIs) were infectious diseases of the urinary system, that caused by different causative agents, including fungi, parasites, viruses, and bacteria. The current study was designed to isolate bacteria from UTI choose E. coli isolates levels interleukin-22 in patients infected with it. Furthermore, studying prevalence type 1 fimbriae (fimH) virulence gene isol...

Type-1 fimbriae are associated with most Salmonella enterica serovars and are an essential factor for host colonization. Mannanoligosaccharides (MOS), a prebiotic that is agglutinated by type-1 fimbriae, are proposed for the control of enterobacteria colonization and may be an alternative to Salmonella control in pigs. The aim of this study was to evaluate the capability of porcine Salmonella s...

INTRODUCTION Vaginitis is one of the most common reasons women visit a gynecologist. Escherichia coli has been isolated from women with vaginitis, but its role as a vaginal infection aetiological agent is controversial. This study aimed to detect virulence genes and determine the antimicrobial susceptibility of E. coli strains isolated from monomicrobial and polymicrobial cultures collected fro...

background: escherichia coli is the most causative agent of urinary tract infections (utis). apart from all human infectious diseases, uti have a high prevalence and in most cases, escherichia coli is a dominance bacterium which can cause pyelonephritis and cystitis. the aim of the study was to determine the occurrence of some virulence genes expressing fimbriae, production of hemolysin and aer...