BACKGROUND The pressure drop-flow relations in myocardial bridges and the assessment of vascular heart disease via fractional flow reserve (FFR) have motivated many researchers the last decades. The aim of this study is to simulate several clinical conditions present in myocardial bridges to determine the flow reserve and consequently the clinical relevance of the disease. From a fluid mechanic...

Over 200 prosthesis using adhesive resin have been set for three years from 1982 to 1985 in our clinic. The patients were recalled and investigated the prognosis of them. The following results were obtained: 1. Adhesion bridges accounted for more than 80% among them and number of posterior bridges has been increased in every year. 2. Adhesion splints have been mainly used for periodontal splint...

The HIV envelope glycoprotein gp120 contains nine disulphide bridges and is highly glycosylated, carrying on average 24 N-linked glycans. Using a probability calculation, we here demonstrate that there is a co-localization of disulphide bridges and N-linked glycans in HIV-1 gp120, with a predominance of N-linked glycans in close proximity to disulphide bridges, at the C-terminal side of the inv...

Halophilic proteins have greater abundance of acidic over basic and very low bulky hydrophobic residues. Classical electrostatic stabilization was suggested as the key determinant for halophilic adaptation of protein. However, contribution of specific electrostatic interactions (i.e. salt-bridges) to overall stability of halophilic proteins is yet to be understood. To understand this, we use Ad...

Quantum calculations on the voltage sensing domain (VSD) of the Kv1.2 potassium channel (pdb: 3Lut)have been carried out on a 904 atoms subset of the VSD, plus 24 water molecules. Side chains pointing away from the center of the VSD were truncated; S1,S2,S3 end atoms were were fixed (all calculations); S4 end atoms could be fixed or free. Open conformations (membrane potentials>= 0) closely mat...

The following paper describes the investigation of two old bridges over inland waterways in Germany under a possible ship impact. Both the numbers of ship impacts against bridges in Germany and the structural description of the bridges has been intensively dealt with. The investigation is based on probabilistic calculations to take into consideration the uncertainty of a possible impact and the...

This paper presents a new bridge management system (J-BMS). It is integrated with a concrete bridge rating expert system that can be used to evaluate the serviceability of existing concrete bridges. The proposed J-BMS not only evaluates the performance of bridges, but also offers a rehabilitation strategy based on a combination of maintenance cost minimization and quality maximization. In this ...

In this paper the parametric study is carried out to investigate the effect of number of cells in optimal cost of the non-prismatic reinforced concrete (RC) box girder bridges. The variables are geometry of cross section, tapered length, concrete strength and reinforcement of the box girders and slabs that are obtained using ECBO metaheuristic algorithm. The design is based on AASHTO standard s...

Infrastructures are a key factor for economy. Among them, transportation infrastructures are vital for human life and economy. And within the transportation networks, bridges are key elements for connecting people anddelivering goods. For this reason, bridges have been built sincemany centuries ago, in some way, and the advances (and sometimes geographical expansions!!) of ancient cultures all ...