نتایج جستجو برای: flanking region

تعداد نتایج: 544338  

2017
Yuning Song Tingjun Liu Yong Wang Jichao Deng Mao Chen Lin Yuan Yi Lu Yuxin Xu Haobin Yao Zhanjun Li Liangxue Lai

Sex-determining region Y is a crucial gene that initiates male sex determination in mammals. Mutations of the Sp1-binding site in the 5' flanking region of SRY are associated with clinical male-to-female sex reversal syndrome, although such occurrences are rare and, until now, have not been reported in animal models. In this study, we mutated Sp1-binding sites in the 5' flanking region of the r...

Journal: :Molecular biology of the cell 1998
Y Kang D R Mitchell

Chlamydomonas reinhardtii flagellar regeneration is accompanied by rapid induction of genes encoding a large set of flagellar structural components and provides a model system to study coordinate gene regulation and organelle assembly. After deflagellation, the abundance of a 70-kDa flagellar dynein intermediate chain (IC70, encoded by ODA6) mRNA increases approximately fourfold within 40 min a...

Journal: :Journal of virology 2013
Celia Harrison Tao Jiang Pubali Banerjee Gretchen Meinke Claudia M D'Abramo Brian Schaffhausen Andrew Bohm

Polyomaviruses have repeating sequences at their origins of replication that bind the origin-binding domain of virus-encoded large T antigen. In murine polyomavirus, the central region of the origin contains four copies (P1 to P4) of the sequence G(A/G)GGC. They are arranged as a pair of inverted repeats with a 2-bp overlap between the repeats at the center. In contrast to simian virus 40 (SV40...

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