An increasing number of integrated optical and acoustic intravascular imaging systems have been developed and hold great promise for accurately diagnosing vulnerable plaques and guiding atherosclerosis treatment. However, in any intravascular environment, the vascular lumen is filled with blood, a high-scattering source for optical and high-frequency ultrasound signals. Blood must be flushed aw...

Numerical modeling of sediment transport in reservoirs, especially for sudden events such as flushing, is still a challenging research topic. In the present study, sediment transport and sediment flushing are simulated for a Peruvian reservoir. Situated in the Peruvian Andes, the watershed is affected by high erosion rates and the river carries high amounts of suspended sediment whose estimated...

Treatment with niacin effectively improves multiple lipid parameters and cardiovascular outcomes. Widespread use of niacin, however, is limited by flushing, which is mediated primarily by prostaglandin D2 (PGD2). Laropiprant is a selective PGD2 receptor 1 (DP1) antagonist that reduces objective measures of niacin-induced flushing symptoms upon initiation of therapy and with more chronic use. Re...

The purpose of the present study was to determine the chronology of the pre-implantation embryonic development in Myocastor coypus (coypu). It was carried out by daily colpocytological examination and controlled mating of 33 females. Oocytes and embryos were obtained by flushing from day 0 to day 10 post-coitus (p.c.). On day 1 p.c., oocytes predominated whereas on day 2 p.c. zygotes were predo...

The objective of this study was to assess the LIF (leukemia inhibitory factor) concentration in uterine flushing and serum (ELISA) of women with proven fertility, infertile women and women with recurrent miscarriage. In addition, progesterone level was determined in serum. A decreased production of LIF in the uterine microenvironment was found in states of impaired fertility. With a cut-off poi...

BACKGROUND Three types of totally implantable venous access devices, Ports, are currently in use: titanium, plastic (polyoxymethylene, POM), and mixed (titanium base with a POM shell). Physics theory suggests that the interaction between a non-coring needle (NCN, made of stainless steel) and a plastic base would lead to the stronger material (steel) altering the more malleable material (plastic...

Alcohol dependence (AD) is a complex disorder with environmental and genetic origins. The role of two genetic variants in ALDH2 and ADH1B in AD risk has been extensively investigated. This study tested for associations between nine polymorphisms in ALDH2 and 41 in the seven ADH genes, and alcohol-related flushing, alcohol use and dependence symptom scores in 4597 Australian twins. The vast majo...

1802. Prevalence of KPC-possessing Klebsiella pneumoniae in New York City: Have We Turned the Corner? Marie Abdallah, MD; Olawole Olafisoye, MD; Christopher Cortes, MD; Clayton Charles, MD; Carl Urban, PhD; David Landman, MD; John Quale, MD; Infectious Diseases, SUNY Downstate Medical Center, Brooklyn, NY; Infectious Diseases, New York Hospital Queens, Flushing, NY; Medicine, SUNY Downstate Med...

The delivery mechanisms of labile nutrients (e.g. NO3, DON and DOC) to streams are poorly understood. Recent work has quantified the relationship between storm DOC dynamics and the connectedness of catchment units and between pre-storm wetness and transient groundwater NO3 flushing potential. While several studies have shown N and C flushing during storm events as the important mechanism in the...

BACKGROUND Niacin is widely available over the counter (OTC). We sought to determine the safety of 500 mg immediate release niacin, when healthy individuals use them as directed. METHODS 51 female and 17 male healthy volunteers (mean age 27 years SD 4.4) participated in a randomized placebo-controlled blinded trial of a single dose of an OTC, immediate-release niacin 500 mg (n = 33), or a sin...