A 32-year-old woman, married for 14 years, attended an ante-natal clinic in her second pregnancy. Repeated serological tests for syphilis were positive and she was referred to a special treatment centre for examination and treatment. She gave a history of vaginal discharge and enlarged glands in the neck 9 years previously, but she had obtained no medical advice at that time and the condition h...

– NSAIDs are generally considered to be safe and well tolerated, but, even with the advent of selective COX-2 inhibitors, nephrotoxicity remains a concern. An impaired renal perfusion caused by the inhibition of prostaglandin synthesis is claimed like the more frequent cause of an acute renal failure due to NSAIDs, while a chronic interstitial nephritis or an analgesic nephropathy are believed ...