Hidradenitis suppurativa, dissecting cellulitis of the scalp, acne conglobata and pilonidal sinus ― are four diseases united by similar clinical findings common mechanisms pathogenesis. These conditions often coexist. The primer pathogenetic event is stratum corneum thickening keratin plugging hair follicle ductal isthmus. discovery this mechanism led to association all with term "follicular oc...

BACKGROUND Human follicular fluid contains several substances, such as cytokines and growth factors, which may affect follicular growth and maturation. The present study examines the relative contribution of macrophages and granulosa cells in the production of vascular endothelial growth factor (VEGF) and adrenomedullin in the human ovulatory follicle. METHODS Both follicular fluid samples an...

BACKGROUND A poor quality of oocytes and embryos and a low fertilization rate have been found in polycystic ovary syndrome (PCOS) patients. An inverse association between follicular fluid homocysteine (Hcy) levels and oocyte and embryo quality has also been demonstrated. We examined the relationship between follicular fluid Hcy concentrations and oocyte and embryo quality in PCOS patients under...

OBJECTIVE To investigate the relationship between serum concentrations of inhibin A, inhibin B and estradiol (E(2)) and the number of developing follicles during the administration of exogenous follicle-stimulating hormone (FSH) in various regimens in normo-ovulatory volunteers and to evaluate if inhibins act as suitable markers for the number of developing follicles during ovarian stimulation....

Foxo transcription factors have been implicated in diverse biological processes, including metabolism, cellular stress responses, and aging. Here, we show that Foxo3a-/- female mice exhibit a distinctive ovarian phenotype of global follicular activation leading to oocyte death, early depletion of functional ovarian follicles, and secondary infertility. Foxo3a thus functions at the earliest stag...

Diffuse large B-cell lymphoma and follicular lymphoma are the most common non-Hodgkin lymphomas seen in adults. Follicular lymphomas are derived from germinal centers of lymphatic tissue and are composed of centrocytes and centroblasts arranged into secondary lymphoid follicles with a germinal center. Follicular lymphomas can transform into diffuse large B-cell lymphoma. Follicular lymphoma in ...

Porcine thyroid epithelial cells, isolated and cultured on a type I collagen substrate, formed a monolayered sheet. When the apical surface of the monolayer was further covered with the same collagen substrate, the epithelial cells migrated and formed intercellular follicular lumen-like structures. In addition, a true intracellular follicular lumen sometimes appeared, especially in cells of the...

An elderly woman presented with generalized lymphadenopathy, several systemic symptoms, and splenomegaly. An inguinal lymph node excision revealed a compound picture. One aspect of the lymph node morphology, including cells with follicular T-helper cell phenotype, was most consistent with angioimmunoblastic T-cell lymphoma. The other component, revealing spindle cells forming whorls with immuno...

This research was conducted to study the follicular dynamics, hormonal, biochemical profile and fertility response in acyclic and norgestomet+PMSG treated acyclic buffaloes in summer. The study animals were divided into two groups: group I [control (n=8): no treatment] and II [treatment group (n=15)]. In group II, seven animals were used for follicular biochemical and hormonal profile and eight...

BACKGROUND Follicular lymphoma is characterized by the t(14;18) translocation resulting in constitutive expression of BCL-2 protein; however approximately 10-15% of follicular lymphomas do not express BCL-2 protein, and a small fraction of these cases does not exhibit translocation of the BCL-2 gene either. It is highly debated whether cases of follicular lymphoma without BCL-2 gene rearrangeme...