OBJECTIVE Macrolide antibiotics have anti-inflammatory properties in lung diseases. The aim of this study was to investigate the effect of clarithromycin in pulmonary cellular inflammatory response in mice. METHOD Eight adult Swiss mice were studied. All animals received an intranasal challenge (80 micro L) with dead Pseudomonas aeruginosa (1.0 x 10(12) CFU/mL). Bronchoalveolar lavage was per...

We report Monte Carlo simulations that show both vapor-liquid and closed-loop liquid-liquid equilibrium in a pure substance, for a model fluid that forms orientation-dependent intermolecular bonds. This is the first time that direct evidence of liquid-liquid immiscibility in a pure fluid has been found using exact methods. Because the model is formulated in terms of a tetrahedrally coordinated ...

Grand-canonical transition-matrix Monte Carlo simulation is applied to analyze the effect of molecular association on the vapor–liquid coexistence and interfacial behavior of square-well based dimerizing fluids. Finite-size scaling techniques are implemented in conjunction with histogram reweighting to determine the infinite-system surface tension from a series of finite-size simulations. The e...

.hot metal gas forming of tubes can be used in various industries such as automotive and aerospace industries. in this process tube is formed at elevated temperatures, by using gas instead of fluid pressure. lower required pressure and low power are its advantages in comparison to hydroforming process. in this paper, a hot metal gas bulging process of an aluminum alloy tube has been investigate...

Bioactive PLLA/surface-grafted silica (g-SiO₂) nanocomposite scaffolds were fabricated by solid-liquid phase separation method. And solid PLLA/g-SiO₂ nanocomposite films were prepared by solution casting method. A series of parallel tube-like morphology and internal ladder-like structure of PLLA/g-SiO₂ nanocomposite scaffolds were observed by SEM. The formation of bone-like apatite in the simul...

The peritoneal cavity is a common target of metastatic gastrointestinal and ovarian cancer cells, but the mechanisms leading to peritoneal metastasis have not been fully elucidated. In this study, we examined the roles of cells in peritoneal fluids on the development of peritoneal metastasis. We found that a minor subset of human intraperitoneal cells with CD90(+)/CD45(-) phenotype vigorously g...

Studies of the element contents and isotopic characteristics sulfide minerals from seafloor hydrothermal deposits are a significant method investigating seawater-fluid mixing fluid-rock and/or sediment interactions in systems. The ores Noho field (NHF) Okinawa Trough (OT) consist pyrrhotite, isocubanite, sphalerite, galena, amorphous silica. Rh, Ag, Sb, Tl mostly increase galena as fluid temper...