Abstract Intestinal barrier dysfunction is linked to human IBD and contributes progression of experimental, immune-mediated colitis. Claudin family tight junction proteins are critical determinants epithelial paracellular permeability function. Expression one these, claudin-2, a pore-forming claudin, specifically upregulated in IBD. We have shown that claudin-2 overexpression or, conversely, ch...

0

background: hyponatremia has poor outcomes in other cardiopulmonary disorders, but its predictive value in predicting mortality of patients with acute pulmonary embolism is unknown. so, we evaluate the mortality of inpatients diagnosed with pulmonary embolism (pe) who had hyponatremia at the time of admission. materials and methods: by conducting a cohort study in patients with acute pulmonary ...

backgrounds and aims: the tehran province was subject to the second highest incidence of fatalities due to traffic accidents in 1390. most studies in this field examine rural traffic accidents, but this study is based on the use of logit models and artificial neural networks to evaluate the factors that affect the severity of accidents within the city of tehran. materials and methods: among the...

objective: to record and classify mechanisms of injury and injury severity score (iss) in trauma patients admitted to the largest trauma center in southern iran. methods: this was a prospective cross-sectional study including all the patients who were admitted to nemazee hospital from 2009 to 2010. we recorded the trauma injury information of 1217 patients who were admitted to of emergency room...

the pediatric risk of mortality (prism) score is a measure of illness severity based on abnormalities observed on bedside examination and laboratory assessment at pediatric intensive care unit (picu) admission to predict mortality probability. our study was performed on 205 patients who were admitted to picu of children’s medical center (cmc) over a period of 6 months.data were recorded prospec...

objectives: to investigate the differences in death after receiving emergency services in traffic accidents between urban and rural regions, and decompose factors of the gap in langerood, northern iran. methods: this cross-sectional study was conducted in langrood, northern iran during a 1-year period from 2013 to 2014. the hospital data of traffic crashes were used. data contained those patien...

background respiratory distress syndrome (rds) is considered as one of the most popular prematurity-related respiratory problems and among the most prominent reasons of deaths in preterm infants. objectives brain natriuretic peptide (bnp) is the secret of the volume and pressure overload response of the vessels and decreases due to resistance as well as rises in systemic vessels and also in dec...

background rheumatoid arthritis (ra) is a chronic inflammatory disease with extra- articular involvement. eyes in particular are one of the most common sites of involvement in rheumatoid arthritis. on the other hand, dry eye syndrome is the most common conflict in terms of management. particular studies suggested dry eye has been associated with greater rheumatoid arthritis severity, but its as...