We have already shown that low intensity pulsed ultrasonic treatment increases rabbit radial fracture healing. The present experiment was undertaken to find out the best duration for treatment. A complete transverse fracture was made in the right radial bones of21 adult male rabbits by a Stanley knife. The animals were divided into 4 groups: group 1, control groups 2, 3, and 4, experimental...

BACKGROUND Peperomia pellucida (L.) HBK is consumed as vegetable and used in Cameroonian traditional medicine for the management of diseases and for fracture healing. Therefore the aim of this study was to evaluate the effects of the aqueous whole plant extract of Peperomia pellucida on fracture healing in female Wistar rats. METHODS A drill hole injury was created by inserting a drill bit in...

BACKGROUND We investigated the underlying molecular mechanisms of bone overgrowth after femoral fracture by using high-throughput bioinformatics approaches. METHODS The gene expression profile of GSE3298 (accession number) was obtained from the Gene Expression Omnibus database. Sixteen femoral growth plate samples, including nine samples without fracture and seven fracture samples for seven t...

Introduction: The need for biocompatible and bioactive scaffolds to accelerate the regeneration and repair of fractured bones has been considered for bone tissue engineering applications during recent decades. The new methods were developed to produce scaffolds to improve the tissue quality, size of cavities, control the porosity and increase the scaffold compressive strength u...

The periosteum is a thin membrane that surrounds the outer surface of bones and participates in fracture healing. However, the molecular signals that trigger/initiate the periosteal reaction are not well established. We fractured the rat femoral bone at the diaphysis and fixed it with an intramedullary inserted wire, and the expression of regenerating gene (Reg) I, which encodes a tissue regene...

BACKGROUND The application of indirect reduction techniques has improved fracture-healing and reduced the need for bone-grafting compared with the outcomes of older, direct reduction techniques. We investigated the results of such indirect reduction techniques for the treatment of periprosthetic femoral shaft fractures. METHODS Fifty consecutive patients with a femoral shaft fracture about a ...

BACKGROUND AND PURPOSE The two most common complications of femoral impaction bone grafting are femoral fracture and massive implant subsidence. We investigated fracture forces and implant subsidence rates in embalmed human femurs undergoing impaction grafting. The study consisted of two arms, the first examining the force at which femoral fracture occurs in the embalmed human femur, and the se...

SCIENTIFIC PROBLEM Fractures of the proximal humerus are one of the most common type of fractures. In particular, elderly people are affected due to loss of bone density, i.e. osteoporosis. Biological, anatomical and biomechanical aspects influence the clinical functional results of the operative therapy. For the operative therapy, different osteosynthesis techniques are known. In the last few ...

Percutaneous vertebroplasty (PV) and kyphoplasty (PK) are the 2vertebral augmentation procedures that have emerged as minimally invasive surgical options to treat painful vertebral compression fractures (VCF) during the last 2 decades. VCF may either be osteoporotic or tumor-associated. Two hundred million women are affected by osteoporosis globally. Vertebral fracture may result in acute pain ...

Background: Plastic deformity is a fixed deformity of bones after application of force which is in contrast to elastic deformity, so it remains unchanged. It is a rare condition and is seen more commonly in upper extremity (forearm). Inability to recognize it causes limitation of motion and remaining of angular deformity. It occurs more commonly in children because of flexibility of their bones...