Molecules with unstable isotopes often contain heavy and deformed nuclei thus possess a high sensitivity to parity-violating effects, such as Schiff moments. Currently the best limits on moments are set diamagnetic atoms. Polar molecules quantum-enhanced sensing capabilities, however, can offer better sensitivity. In this work, we consider prototypical 223Fr107Ag molecule, octupole deformation ...

Abstract IBD is characterized by inflammation involving a complex interplay between innate and adaptive immunity, non-immune cells, intestinal microbes. To understand the contributions of immunity to during colitis we have developed chronic model immune-mediated wherein RAG1-/- mice are crossed with expressing TNFAIP3 in epithelial cells (villin-TNFAIP3 mice). These villin-TNFAIP3 x (TRAG) deve...

In this issue, both Dong and Tweardy (page 2637) and Maurer et al (page 2647) offer a detailed functional and biochemical characterization of the Stat5b-RARa fusion protein, which was originally described in a patient with acute promyelocytic leukemia (APL) several years ago (Arnould et al, Hum Mol Genetics. 1999;8:1741-1749). Stat5b is one of 5 genes that have now been identified as fusion par...

We have seen that the BH procedure controls the FDR for multiple testing when the p-values are independent. How can we control the FDR under dependence? Here, we consider the case where the statistics have distribution Y ∼ N (μ,Σ); in the past, we have assumed that Σ = Ip. If the covariance matrix Σ were known, we could reduce to the independent case using the transformation Y ′ = Σ− 1 2Y , so ...