نتایج جستجو برای: free testosterone index

تعداد نتایج: 911857  

Journal: :The Journal of clinical endocrinology and metabolism 2017
Thozhukat Sathyapalan Alan S Rigby Shalender Bhasin Natalie J Thatcher Eric S Kilpatrick Stephen L Atkin

Context Isoflavones found in soy products have a chemical structure similar to estrogen, leading to concerns of an adverse estrogenic effect in men, particularly in those with type 2 diabetes mellitus (T2DM) who have low testosterone levels due to hypogonadism. Objective The primary outcome was change in total testosterone levels. The secondary outcomes were the changes in glycemia and cardio...

Journal: :Clinical chemistry 2000
A H Garde A M Hansen L T Skovgaard J M Christensen

BACKGROUND Concentrations of physiological response variables fluctuate over time. The present study describes within-day and seasonal fluctuations for total cholesterol, dehydroepiandrosterone sulfate (DHEA-S), hemoglobin A(1c) (HbA(1c)), IgA, prolactin, and free testosterone in blood, and estimates within- (CV(i)) and between-subject (CV(g)) CVs for healthy women. In addition, the index of in...

Journal: :The American journal of clinical nutrition 2016
Sunni L Mumford Jorge E Chavarro Cuilin Zhang Neil J Perkins Lindsey A Sjaarda Anna Z Pollack Karen C Schliep Kara A Michels Shvetha M Zarek Torie C Plowden Rose G Radin Lynne C Messer Robyn A Frankel Jean Wactawski-Wende

BACKGROUND Emerging evidence suggests potential links between some dietary fatty acids and improved fertility, because specific fatty acids may affect prostaglandin synthesis and steroidogenesis. OBJECTIVE The objective of this exploratory study was to evaluate associations between total and specific types of dietary fat intake and 1) hormone concentrations and 2) the risk of sporadic anovula...

2003
Anne McTiernan Kumar B. Rajan Shelley S. Tworoger Melinda Irwin Leslie Bernstein Richard Baumgartner Frank Gilliland Frank Z. Stanczyk Yutaka Yasui Rachel Ballard-Barbash

Purpose: Overweight and obese women with breast cancer have poorer survival compared with thinner women. One possible reason is that breast cancer survivors with higher degrees of adiposity have higher concentrations of tumor-promoting hormones. This study examined the association between adiposity and concentrations of estrogens, androgens, and sex hormone–binding globulin (SHBG) in a populati...

Journal: :Clinical journal of the American Society of Nephrology : CJASN 2011
Mahmut Ilker Yilmaz Alper Sonmez Abdul Rashid Qureshi Mutlu Saglam Peter Stenvinkel Halil Yaman Tayfun Eyileten Kayser Caglar Yusuf Oguz Abdullah Taslipinar Abdulgaffar Vural Mahmut Gok Hilmi Umut Unal Mujdat Yenicesu Juan Jesús Carrero

BACKGROUND AND OBJECTIVES Deterioration of kidney function impairs testosterone production, with hypogonadism being common in men with chronic kidney disease (CKD). In nonrenal populations, testosterone is suggested to participate in the atherosclerotic process. In male dialysis patients, we showed that low testosterone increases the risk of mortality. We here studied plausible links among test...

Journal: :The Prostate 2015
Sarah B Peskoe Corinne E Joshu Sabine Rohrmann Katherine A McGlynn Sarah J Nyante Gary Bradwin Adrian S Dobs Norma Kanarek William G Nelson Elizabeth A Platz

BACKGROUND The association between serum sex steroid hormones and PSA in a general population has not been described. METHODS Included were 378 men aged 40-85 years who participated in the National Health and Nutrition Examination Survey in 2001-2004, who did not have a prostate cancer diagnosis, and had not had a recent biopsy, rectal examination, cystoscopy, or prostate infection or inflamm...

2012
Ming Liao Xianghua Huang Yong Gao Aihua Tan Zheng Lu Chunlei Wu Youjie Zhang Xiaobo Yang Haiying Zhang Xue Qin Zengnan Mo

BACKGROUND Testosterone is essential for the regulation of erectile physiology, but the relationship between low testosterone and erectile dysfunction (ED) has not been firmly established. PURPOSE To examine the association between serum total, free and bio-available testosterone and ED in a population-based sample. METHODS A consecutive series of 1776 men aged 20-77 participated in the rou...

2011
Shalender Bhasin Guneet K. Jasjua Michael Pencina Ralph D’Agostino Andrea D. Coviello Ramachandran S. Vasan Thomas G. Travison

OBJECTIVE The association between total testosterone and metabolic syndrome has prompted speculation that low testosterone contributes to the pathophysiology of metabolic syndrome in men. We determined whether testosterone or sex hormone-binding globulin (SHBG) is independently associated with the risk of metabolic syndrome. RESEARCH DESIGN AND METHODS Cross-sectional relationships of hormone...

2011
Claes Ohlsson Henri Wallaschofski Kathryn L. Lunetta Lisette Stolk John R. B. Perry Annemarie Koster Ann-Kristin Petersen Joel Eriksson Terho Lehtimäki Ilpo T. Huhtaniemi Geoffrey L. Hammond Marcello Maggio Andrea D. Coviello Luigi Ferrucci Margit Heier Albert Hofman Kate L. Holliday John-Olov Jansson Mika Kähönen David Karasik Magnus K. Karlsson Douglas P. Kiel Yongmei Liu Östen Ljunggren Mattias Lorentzon Leo-Pekka Lyytikäinen Thomas Meitinger Dan Mellström David Melzer Iva Miljkovic Matthias Nauck Maria Nilsson Brenda Penninx Stephen R. Pye Ramachandran S. Vasan Martin Reincke Fernando Rivadeneira Abdelouahid Tajar Alexander Teumer André G. Uitterlinden Jagadish Ulloor Jorma Viikari Uwe Völker Henry Völzke H. Erich Wichmann Tsung-Sheng Wu Wei Vivian Zhuang Elad Ziv Frederick C. W. Wu Olli Raitakari Anna Eriksson Martin Bidlingmaier Tamara B. Harris Anna Murray Frank H. de Jong Joanne M. Murabito Shalender Bhasin Liesbeth Vandenput Robin Haring

Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a meta-analysis of genome-wide association data in 8,938 men from seven cohorts and followed up the genome-wide significant findings in one in silico (n = 871) and two de novo r...

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