Aging is associated with microstructural white matter (WM) changes. WM microstructural characteristics, measured with diffusion tensor imaging (DTI), are different in normal appearing white matter (NAWM) and WM hyperintensities (WMH). It is largely unknown how the microstructural properties of WMH are associated with cognition and if there are regional effects for specific cognitive domains. We...

Executive control functions (ECFs) have become an important topic in the cognitive sciences in the past 40 years. The number of publications has steadily increased, and in the last decade, studies have been conducted in one of the best models of human cognition: the old-world macaque monkey. Here, we review recent studies in the monkey that have contributed to our understanding of the neuronal ...

This PET study explored the neural substrate of both dual-task management and integration task using single tasks that are known not to evoke any prefrontal activation. The paradigm included two simple (visual and auditory) discrimination tasks, a dual task and an integration task (requiring simultaneous visual and auditory discrimination), and baseline tasks (passive viewing and hearing). Data...

The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control-the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they s...

The notion that there is a relationship between frontal lobe damage and aggression has been part of clinical lore for more than 50 years. However, although there is evidence for an association between general brain dysfunction and aggressive behavior, much of the evidence for a specific relationship between frontal lobe dysfunction and aggression has consisted of case reports. This article begi...

Background: Although some studies of the C1 ERP component have revealed perceptual variation in pregnant women, source localization has not yet been determined this group. We aimed to investigate women using sLORETA tools Net Station software. Method: A total 36 participants were recruited and divided between control (n=18) group (n=18). data collected 128 nets during a visual oddball paradigm ...