We aimed to analyze the effects of chronic and acute exercise on circulating HbA1c and fructosamine levels. In patients with type 1 diabetes, exercise has not consistently been shown to improve glycemic control, as measured using HbA1c levels. Participation in competitive sports may even worsen glycaemic control. Free radicals and oxidative stress markers are known to increase during acute exer...

RESEARCH DESIGN AND METHODS—There was a cross-sectional study of 1,600 participants (227 with a history of diabetes and 1,323 without) from the Atherosclerosis Risk in Communities (ARIC) Study, a community-based population. We conducted logistic regression analyses of the associations of diabetes-specific tertiles of fructosamine, glycated albumin, 1/ (1,5-AG), fasting glucose, and HbA1c with p...

Protein glycation and the formation of AGEs (advanced glycation end-products) and cross-links have been hypothesized to play a role in the pathogenesis of age- and diabetes-related complications. The discovery that FN3K (fructosamine 3-kinase) results in protein deglycation upon phosphorylation of glucose-derived Amadori products suggests that intracellular glycation could be deleterious under ...

Objectives: To investigate the effect of long term intake of traditionally used hypolipidemic drugs, atorvastatin and fenofibrate, on cholesterol derived products including steroidal hormones, vitamin D, and bile salts. Materials and methods: Male Wistar albino rats were divided into four groups including a normal control group and the other groups were rendered diabetic dyslipidemic (DD) and r...