We assessed gastric myoelectric functioning in patients with various gastrointestinal symptoms and to determine the utility of electrogastrography in differentiating specific disease entities. Electrogastrography with a water load was performed in 101 patients with reflux disease, 55 patients with active gastric ulcer, 59 patients with functional dyspepsia, and 30 controls. Upper gastrointestin...

Somatosensory amplification is the tendency to report somatic sensations as intense and disturbing. Alexithymia is a personality construct characterized by difficulty recognizing emotions and a tendency to focus on external events and bodily sensations. The association of somatosensory amplification and alexithymia with functional symptoms was assessed in 111 patients with functional dyspepsia ...

background dyspepsia is a common disorder that can present many clinical dilemmas in patient management. although not usually life-threatening, its symptoms such as abdominal pain, heartburn, early satiety and postprandial fullness can have a significant negative impact on patients' quality of life. objectives the aim of this study was to determine the prevalence of dyspepsia and its associated...

The clinical outcome of Helicobacter pylori infection has been particularly associated with virulence genotypes. These genotypes are useful as molecular markers in the identification of patients that are infected and at high risk for developing more severe gastric pathologies. Our main objective was to determine the prevalence of virulence genotypes cagA, vacA, iceA and babA2 of H. pylori, in p...

BACKGROUND It remains controversial as to whether delayed gastric emptying in functional dyspepsia is associated with a specific symptom pattern, and it is unknown if gastric emptying in functional dyspepsia is a driver of impaired health related quality of life (HRQOL). We aimed to evaluate the relationship between functional dyspepsia symptoms, gastric emptying, and HRQOL. METHODS US patien...

Dyspepsia is a syndrome consisting of epigastric pain, burning, fullness, discomfort, early satiety, nausea, vomiting and belching. Functional dyspepsia (FD) is diagnosed if upper gastrointestinal endoscopy does not show structural abnormality explaining these symptoms. 8%-30% and 8%-23% of Asian people suffer from of uninvestigated dyspepsia and FD, respectively. Most patients with uninvestiga...

Dyspepsia refers to a condition of impaired digestion which has a yearly incidence of approximately 1%, and the prevalence of around 20-30%. Although the etiology of dyspepsia varies, an organic cause is found in only 40% of the patients. In the differential diagnosis of dyspepsia, cardiac, hepatobiliary, pancreatic, and intestinal disorders and gastroesophageal reflux disease can be eliminated...