A 38-year-old woman, gravida 3, para 1 with a history of a left salpingectomy for an ectopic pregnancy was admitted for treatment of a presumed ectopic pregnancy. Transvaginal sonography revealed an ill-defined gestational sac and fetal heart beat within the fundal myometrium adjacent to the left cornua. Laparoscopy was performed for a suspected left cornual pregnancy or intramural pregnancy. A...

Gastric volvulus is a significant, rare cause of non-bilious vomiting and consists of a pathological rotation of the stomach of more than 180° around the axis without obstruction of the gastrointestinal tract. A definitive diagnosis is made with upper radiological gastrointestinal studies. Treatment may be conservative or surgical with anterior and fundal gastropexy in patients with ingravescen...

PURPOSE To screen the paired box gene 6 (PAX6) gene in irido-fundal coloboma. METHODS The entire coding region of PAX6 including intron-exon boundaries was amplified from cases (n=30) and controls (n=30). All sequences were analyzed against the ensemble sequence (ENSG00000007372) for PAX6. RESULTS DNA sequence analysis of patients and controls revealed a total of three nucleotide changes (g...

KEY CLINICAL MESSAGE Placenta percreta (with bladder invasion) is a rare obstetric condition with the risk of massive intraoperative hemorrhage. In these cases, the combination of a transverse uterine fundal incision and retrograde cesarean hysterectomy could be useful to minimize maternal hemorrhage and avoid severe bladder injury.

Aims Clinical management of the second stage labor and effectiveness preventive measures for severe perineal tears are controversial. The aim this study was to evaluate effect using uterine fundal pressure during delivery on obstetric anal sphincter injury (OASI), among primiparous women three-dimensional (3D) transperineal ultrasonography. Methods A total 73 who had their first vaginal birth w...

OBJECTIVE To describe the prevalence and phenotypic characteristics of small eyes in the European Prospective Investigation of Cancer (EPIC)-Norfolk Eye Study. DESIGN Community cross-sectional study. SETTING East England population (Norwich, Norfolk and surrounding area). PARTICIPANTS 8033 participants aged 48-92 years old from the EPIC-Norfolk Eye Study, Norfolk, UK with axial length mea...