BACKGROUND The development of the Drosophila eye imaginal disc requires complex epithelial rearrangements. Cells of the morphogenetic furrow are apically constricted and this leads to a physical indentation in the epithelium. Posterior to the furrow, cells start to rearrange into distinct clusters and eventually form a precisely patterned array of ommatidia. These morphogenetic processes includ...

Precise cleavage furrow positioning is required for faithful chromosome segregation and cell fate determinant distribution. In most metazoan cells, contractile ring placement is regulated by the mitotic spindle through the centralspindlin complex, and potentially also the chromosomal passenger complex (CPC). Drosophila neuroblasts, asymmetrically dividing neural stem cells, but also other cells...

Shortage and salinity of irrigation water are two major constraints that influence rapeseed production in arid and semi-arid regions of central and southern Iran. In this study, effects of deficit irrigation with different salinity levels and planting methods (in-furrow and on-ridge) as strategies for coping with water and salinity stresses on yield and yield quality of rapeseed were invest...

Ventral furrow formation is a key morphogenetic event during Drosophila gastrulation that leads to the internalization of mesodermal precursors. While genetic analysis has revealed the genes involved in the specification of ventral furrow cells, few of the structural proteins that act as mediators of ventral cell behavior have been identified. A comparative proteomics approach employing differe...

Irrigation water is limiting for crop production in arid and semi-arid areas. Furthermore, excess nitrogen (N) application is a source of groundwater contamination. Partial root drying irrigation (PRD) can be used as water saving technique and a controlling measure of groundwater N contamination. The objectives of this investigation were to evaluate the effect of ordinary furrow irrigation (OFI...

this research was carried out to evaluate the effects of irrigation methods and n fertilizer rates on the quantity and quality of sugar beet in ekbatan research station during 2001 and 2002. experiment was performed in split-plot with 3 replications and 15 treatments. treatments included 3 irrigation systems: sprinkler (solid set)، furrow (hydroflum) and drip (tape: 508-20-500) in main plots an...

During cytokinesis, a specialized set of proteins is recruited to the equatorial region between spindle poles by microtubules and actin filaments, enabling furrow assembly and ingression before cell division. We investigate the mechanisms underlying regional specialization of the cytoskeleton in HeLa cells undergoing drug-synchronized monopolar cytokinesis. After forced mitotic exit, the cytosk...

The initial steps of pattern formation in the developing Drosophila eye involve the coordination of cell cycles, changes in cell shape, and the specification of the R8 photoreceptor cell. These events begin several cell rows ahead of the morphogenetic furrow and are positively regulated by secreted signaling proteins and the proneural HLH transcription factor atonal (ato). Two HLH regulatory pr...

During anaphase, distinct populations of microtubules (MTs) form by either centrosome-dependent or augmin-dependent nucleation. It remains largely unknown whether these different MT populations contribute distinct functions to cytokinesis. Here we show that augmin-dependent MTs are required for the progression of both furrow ingression and abscission. Augmin depletion reduced the accumulation o...