background: development of an effective vaccine is highly needed in order to restrict the aids pandemic. dna vaccines initiate both arms of immunity without the potential of causing disease. hiv-1 p24 and gp41 (gag and env) proteins play important roles in viral pathogenesis and are effective candidates for immune induction and vaccine design. objective: in this study, new dna vaccine candidate...

Bioethanol has been considered as a more sustainable alternative for fossil fuels, and it used drop-in fuel mixture. In this paper, the autoxidation properties of real kerosene well single, binary ternary surrogates with presence ethanol are investigated first time. A simplified python code is proposed to predict pressure drop PetroOXY method that was assessing properties. The experimental resu...

The density and viscosity of propane mixed with 66/34 trans/cis-decahydronaphthalene were measured over a wide range of temperatures (323 – 423K), pressures (2.5-208 bar), and compositions (0-65 mol% propane). For conditions giving two phases, the composition of the dense phase was measured in addition to the density and viscosity. The modified SanchezLacombe equation of state (MSLEOS) was used...

Background: D-Phenylglycine aminotransferase (D-PhgAT) is highly beneficial in pharmaceutical biotechnology. Like many other enzymes, D-PhgAT suffers from low stability under harsh processing conditions, poor solubility of substrate, products and occasional microbial contamination. Incorporation of miscible organic solvents into the enzyme’s reaction is considered as a solution...

The comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC × GC/TOFMS) has been used to characterize a crude oil and a source rock extract sample. During the process, a series of pairwise components between monocyclic alkanes and mono-aromatics have been discovered. After tentative assignments of decahydronaphthalene isomers, a series of alkyl decalin isomers have...

A convergent, stereocontrolled route to either antipode of the cell adhesion inhibitor, peribysin E, has been achieved from carvone. Highlights of the synthesis include a Diels-Alder reaction to generate a cis-decalin framework, followed by semipinacol-type ring contraction to secure the stereochemistry of the C7 quaternary center. Potential mechanistic pathways for the critical ring contractio...