The main purposes of this study were to 1) investigate the dosimetric quality of uniform scanning proton therapy planning (USPT) for prostate cancer patients with a metal hip prosthesis, and 2) compare the dosimetric results of USPT with that of volumetric-modulated arc therapy (VMAT). Proton plans for prostate cancer (four cases) were generated in XiO treatment planning system (TPS). The beam ...

We assessed the clinical benefit of combining volumetric-modulated arc therapy (VMAT) and hypofractionated radiotherapy (HF-RT) considering incidence radiation-related toxicities. After a retrospective review for breast cancer patients treated with adjuvant RT between 2005 2017, total 4209 three-dimensional conventional fractionation (CF-3D, 50.4 Gy/28 fractions) 1540 HF-RT (768 received HF-3D;...

PURPOSE Volumetric modulated arc therapy (VMAT) involves the simultaneous use of dynamic multileaf collimator (DMLC) techniques and gantry arcing; appropriate quality assurance is therefore required. This article describes the development and implementation of procedures for commissioning VMAT on a commercial linear accelerator (Elekta PreciseBeam VMAT with MLCi and Beam Modulator heads). MAT...

OBJECTIVES Simultaneous integrated boost (SIB) for prostate cancer allows increases in tumor control probability while respecting normal tissue dose constraints. Biological optimization functions that optimize based on treatment outcome can be used to create SIB prostate plans. This study investigates the feasibility of biologically optimized volumetric modulated arc therapy (VMAT) for SIB pros...

PURPOSE To investigate the critical structure sparing achievable by biological optimization for modulated volumetric arc (VMAT) of head and neck (H&N) cancer. METHODS Ten H&N VMAT patients who were originally planned and treated with simultaneous integrated boost technique using dose-volume based optimization, were selected. For each patient, a new VMAT plan was generated using the generalize...

Prior to the use of detectors, characteristics comparison study was performed and baseline established. In patient specific QA, the portal dosimetry mean values of area gamma, average gamma and maximum gamma were 1.02, 0.31 and 1.31 with standard deviation of 0.33, 0.03 and 0.14 for IMRT and the corresponding values were 1.58, 0.48 and 1.73 with standard deviation of 0.31, 0.06 and 0.66 for VMA...

Journal of Medical Physics ¦ Volume 42 ¦ Issue 2 ¦ April-June 2017 100 We highly appreciate your comments. It is well known that there are considerable target position uncertainties during breast radiotherapy. These uncertainties result from respiratory motions, tissue and organ deformation, daily patient setup, and other causes. Respiratory gating and breath control can reduce the target posit...

Non-coplanar radiation beams are often used in three-dimensional conformal and intensity modulated radiotherapy to reduce dose to organs at risk (OAR) by geometric avoidance. In volumetric modulated arc radiotherapy (VMAT) non-coplanar geometries are generally achieved by applying patient couch rotations to single or multiple full or partial arcs. This paper presents a trajectory optimization m...

OBJECTIVES To compare the target volume coverage and doses to organs at risks (OARs) using three techniques that simultaneous integrated boost (SIB) in whole-breast irradiation (WBI) after breast-conserving surgery, including intensity-modulated radiation therapy (IMRT), IMRT plus an electron boost (IMRT-EB), and volumetric-modulated arc therapy (VMAT). METHODS A total of 10 patients with ear...

VMAT is an important tool in the treatment of head and neck cancers, many of which also require treatment to the supraclavicular lymph nodes. However, full VMAT arcs treating this nodal region necessarily cause entrance beam to pass through patients' shoulders. Thus, interfractional variations in shoulder position may cause unwanted dose perturbations. To assess this possibility, six patients u...