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We present a high-level programming language for the specification of procedural models. AL — an acronym for Animation Language — provides specialized programming constructs, data types, and operations for modeling, animation and rendering. In addition, it introduces a new mechanism for interaction with procedural models called articulation functions. AL extends and generalizes the mechanisms a...
The Innocastle project was developed within the framework of Interreg Europe programme, which aims to support local and regional governments in develop deliver better policy. takes place between June 2018 November 2022. This article presents issues addressed by project, approach improving policy instruments results until now.
This article introduces results about probabilistic parsing enhanced with a word clustering approach based on a French syntactic lexicon, the Lefff (Sagot, 2010). We show that by applying this clustering method on verbs and adjectives of the French Treebank (Abeillé et al., 2003), we obtain accurate performances on French with a parser based on a Probabilistic ContextFree Grammar (Petrov et al....
A major obstacle to the efficient production of antibody conjugates for therapy and diagnosis is the non-ideal performance of commonly used chemical methods for the attachment of effector-molecules to the antibody of interest. Here we demonstrate that this limitation can be simply addressed using 3,4-substituted maleimides to bridge and thus functionalize disulfide bonds to generate homogeneous...
During a germinal center reaction, random mutations are introduced into immunoglobulin V genes to increase the affinity of antibody molecules and to further diversify the B cell repertoire. Antigen-directed selection of B cell clones that generate high affinity surface Ig results in the affinity maturation of the antibody response. The mutations of Ig genes are typically basepair substitutions,...
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