Pharmacokinetic/pharmacodynamic (PK/PD) modeling is the dominant approach for dose and dosing regimen selection in drug discovery and development. It has the unique capability of incorporating constraints imposed by the underlying pharmacology/pathophysiology and offers a rich body of behaviors for modeling the relationship between drug dose and the time course of drug disposition and effect. T...

In this paper, Gait Energy Image (GEI) has constructed to apply Principal Component Analysis (PCA) with and without Radon Transform (RT). The Radon Transform is used to detect features within an image and PCA is used to reduce dimension of the images without much loss of information. The side view of slow walk; fast walk and carrying a ball walk have been selected from the CMU MoBo database for...

A significant Genotype by Environment Interaction (GEI) makes selection of stable genotypes difficult. This study was conducted to establish the effect GEI on yield Common bean and reduce complaints under performances. Eighteen (18) were assessed for variation in gene expression linked predictors three different districts Mbeya region (Mbarali, Mbozi districts). Regression, pooled ANOVA AMMI bi...

Actualmente se reconoce que el sector constructor es uno de los principales generadores residuos construcción y demolición (RCD) emisiones gases efecto invernadero (GEI) a nivel mundial. Si bien nacional existe la Resolución 0472 2017 para llevar cabo una adecuada gestión RCD, importante analizar influencia del cumplimiento esta norma en generación posible disminución GEI. Por razón, presente i...

We investigated the effect of unpredictable feeding times on feeding activity and body mass gain in fast growing Japanese quail (Cotumix c. japonica) from 7 to 31 d of age. Quail chicks were subjected to a long day length (18L:6D) with ad libitum food during (1) 17.5 h of the light period, starting 0.5 h after lights-on (group A, n = 14), (2) 6 h of the light period, starting 0.5 h after lights...

Soybean [Glycine max (L.) Merrill] is an important crop in southern Africa where it cultivated a wide range of agro-ecologies. Both spatial and seasonal variability high the region. As result, breeders aim to release varieties with fine balance productivity potential stability. Genotype × environment interaction (GEI) limits selection superior genotypes heterogeneous environments consequently s...

GGE biplot technique is one of the most appropriate methods for investigating genotype x environment interaction. A total twenty Egyptian cotton genotypes were tested to evaluate stability and adaptability during two agricultural years at four environments using randomized complete block design with six replications. The analysis variance showed that effect environments, years, genotypes, was h...

The experiment was conducted to evaluate the nature and extent of genotype environment interactions, select stable high yielding taro genotypes for fresh storage corm yield, related traits identify most representative discriminating in southwest Ethiopian regions. study tested across four environments (Jimma, Agaro, Gera, Metu) two cropping seasons Ethiopia. Nine selected promising one standard...

In the Mediterranean Basin, potato (Solanum tuberosum L.) is a major staple crop, yield performance of which can vary dramatically based on pedo-climatic conditions and genotype. Hence, dissecting genotype × environment interaction (GEI) in this region mandatory for setup high-yielding stable genotypes, also considering its importance local breeding development protected geographical identifica...