نتایج جستجو برای: gene activators

تعداد نتایج: 1148624  

Journal: :Cell 1999
Edio Maldonado Michael Hampsey Danny Reinberg

complex. This complex mediates the response to tran-scriptional activators as well as repressors. Other co-activators have also been identified. These include TFIIA, which stabilizes DNA-TBP binding, and factors that affect nucleosome structure, including histone ace-Facultad de Medicina Universidad de Chile tyltransferases and ATP-dependent chromatin remodel-ing complexes. Eukaryotic repressor...

Journal: :"Protein Engineering, Design and Selection" 1987

Journal: :Nucleic Acids Research 2006

Journal: :Molecular pharmacology 2007
C Y Ung H Li C W Yap Y Z Chen

Pregnane X receptor (PXR) regulates drug metabolism and is involved in drug-drug interactions. Prediction of PXR activators is important for evaluating drug metabolism and toxicity. Computational pharmacophore and quantitative structure-activity relationship models have been developed for predicting PXR activators. Because of the structural diversity of PXR activators, more efforts are needed f...

Journal: :Journal of the agricultural chemical society of Japan 1925

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