نتایج جستجو برای: genealogical parameters

تعداد نتایج: 580615  

Journal: :Social studies of science 2008
Alondra Nelson

This paper considers the extent to which the geneticization of 'race' and ethnicity is the prevailing outcome of genetic testing for genealogical purposes. The decoding of the human genome precipitated a change of paradigms in genetics research, from an emphasis on genetic similarity to a focus on molecular-level differences among individuals and groups. This shift from lumping to splitting spu...

Journal: :American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004
Maria Karayiorgou Marie Torrington Gonçalo R Abecasis Herman Pretorius Brian Robertson Sean Kaliski Stephen Lay Christina Sobin Natalie Möller S Laura Lundy Maude L Blundell Joseph A Gogos J Louw Roos

Founder populations hold tremendous promise for mapping genes for complex traits, as they offer less genetic and environmental heterogeneity and greater potential for genealogical research. Not all founder populations are equally valuable, however. The Afrikaner population meets several criteria that make it an ideal population for mapping complex traits, including founding by a small number of...

Journal: :Theoretical population biology 2008
Frederick A Matsen Steven N Evans

Recent statistical and computational analyses have shown that a genealogical most recent common ancestor (MRCA) may have lived in the recent past [Chang, J.T., 1999. Recent common ancestors of all present-day individuals. Adv. Appl. Probab. 31, 1002-1026. 1027-1038; Rohde, D.L.T., Olson, S., Chang, J.T., 2004. Modelling the recent common ancestry of all living humans. Nature 431, 562-566]. Howe...

2013
Claudia Moreau Jean-François Lefebvre Michèle Jomphe Claude Bhérer Andres Ruiz-Linares Hélène Vézina Marie-Hélène Roy-Gagnon Damian Labuda

For years, studies of founder populations and genetic isolates represented the mainstream of genetic mapping in the effort to target genetic defects causing Mendelian disorders. The genetic homogeneity of such populations as well as relatively homogeneous environmental exposures were also seen as primary advantages in studies of genetic susceptibility loci that underlie complex diseases. Europe...

2003
C. S. Srinivasan Colin Thirtle Paolo Palladino

Genealogical data have been used very widely to construct indices with which to examine the contribution of plant breeding programmes to the maintenance and enhancement of genetic resources. In this paper we use such indices to examine changes in the genetic diversity of the winter wheat crop in England and Wales between 1923 and 1995. We find that, except for one period characterized by the do...

2018
Henri Kauhanen Deepthi Gopal Tobias Galla Ricardo Berm'udez-Otero

Different structural features of human language change at different rates and thus exhibit different temporal stabilities. Existing methods of linguistic stability estimation depend upon the prior genealogical classification of the world’s languages into language families; these methods result in unreliable stability estimates for features which are sensitive to horizontal transfer between fami...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید