نتایج جستجو برای: genetic adjuvant

تعداد نتایج: 656950  

A. Khorasani H. Keyvanfar H. Mahravani H. Soleimanjahi O. Madadgar,

Foot-and-mouth disease is an important viral disease of cloven-hoofed animals. Inactivated whole particle virus vaccines are still widely used in prophylactic vaccination campaigns. The choice of adjuvant is a very important factor in enhancing immune responses and the efficacy of inactivated vaccines. Montanide ISA 61 VG is a new ready-to-use mineral oil-based adjuvant developed by SEPPIC Inc....

سلیمانی, سینا , شاهسوندی, شهلا , لطفی, محسن , مددگار, امید , مهروانی, همایون ,

Background: In the last decade due to emerge and remerge of influenza viruses, quality improvement of vaccines to increase immune responses in target populations have been more necessary. The potential of biologic adjuvant to stimulate and induce immune system is the basis of modern researches in prevention and controlling program of infectious diseases. In this study, the effect of the coding ...

Fatemeh Homaei Shandiz, Fatemeh Varshoee Tabrizi, Kamran Ghafarzadegan Mohammad Khagedaloee Mohammad-Reza Ghavam Nassiri

  Background and Objective: Esophageal cancer especially squamous cell carcinoma (SCC) is one of the most common gastro intestinal malignancies in north part of Iran (Khorasan). The standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. Then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. Sever...

Journal: :Current Genomics 2008
Clorinda Schettino Maria A Bareschino Paolo Maione Antonio Rossi Fortunato Ciardiello Cesare Gridelli

Although notable progress has been made in the treatment of non-small-cell lung cancer (NSCLC) in recent years, this disease is still associated with a poor prognosis. Despite early-stage NSCLC is considered a potentially curable disease following complete resection, the majority of patients relapse and eventually die after surgery. Adjuvant chemotherapy prolongs survival, altough the absolute ...

2014
Hanna L. Thim Stéphane Villoing Marian McLoughlin Karen Elina Christie Søren Grove Petter Frost Jorunn B. Jørgensen

Most commercial vaccines offered to the aquaculture industry include inactivated antigens (Ag) formulated in oil adjuvants. Safety concerns are related to the use of oil adjuvants in multivalent vaccines for fish, since adverse side effects (e.g., adhesions) can appear. Therefore, there is a request for vaccine formulations for which protection will be maintained or improved, while the risk of ...

2015
Yasushi Hamaya Carla Guarinos Stephanie S. Tseng-Rogenski Moriya Iwaizumi Ritabrata Das Rodrigo Jover Antoni Castells Xavier Llor Montserrat Andreu John M. Carethers Jian-Xin Gao

Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) is a genetic signature found in up to 60% of colorectal cancers (CRCs) that is caused by somatic dysfunction of the DNA mismatch repair (MMR) protein hMSH3. We have previously shown in vitro that recognition of 5-fluorouracil (5-FU) within DNA and subsequent cytotoxicity was most effective when both hMutSα (hMSH2-hM...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006
Martin J van den Bent Antoine F Carpentier Alba A Brandes Marc Sanson Martin J B Taphoorn Hans J J A Bernsen Marc Frenay Cees C Tijssen Wolfgang Grisold Laslo Sipos Hanny Haaxma-Reiche Johannes M Kros Mathilde C M van Kouwenhoven Charles J Vecht Anouk Allgeier Denis Lacombe Thierry Gorlia

PURPOSE Anaplastic oligodendrogliomas are more responsive to chemotherapy than high-grade astrocytomas. We investigated, in a multicenter randomized controlled trial, whether adjuvant procarbazine, lomustine, and vincristine (PCV) chemotherapy improves overall survival (OS) in newly diagnosed patients with anaplastic oligodendrogliomas or anaplastic oligoastrocytomas. PATIENTS AND METHODS The...

Journal: :Lancet Oncology 2021

Breast cancer is increasingly prevalent in older adults and a substantial part of routine oncology practice. However, management breast this population challenging because the disease highly heterogeneous there insufficient evidence specific to adults. Decision making should not be driven by age alone but involve geriatric assessments plus careful consideration life expectancy, competing risks ...

2009
M L Conrad A Ö Yildirim S S Sonar A Kılıç S Sudowe M Lunow R Teich H Renz H Garn

INTRODUCTION The most widely used protocol for the induction of experimental allergic airway inflammation in mice involves sensitization by intraperitoneal (i.p.) injections of the antigen ovalbumin (OVA) used in conjunction with the adjuvant aluminium hydroxide (alum). Although adjuvants are frequently used, there are questions regarding the necessity of alum for murine asthma studies due to t...

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