Various functioning and non-functioning tumors arise from endocrine glands in both the sporadic and familial forms and pathophysiology of the tumors is variable due to differences in the sort of tumor-bearing endocrine organs and in the amount of hormones released. In this paper, gene abnormalities in growth hormone (GH)-secreting pituitary adenoma, ectopic GHRH-producing tumor, multiple endocr...

1. Department of Medical Imaging, AZ KLINA, Brasschaat, Belgium Background: A 66-year-old man, known with nephrocalcinosis in his medical history, was complaining of weight loss, pain at the level of the kidneys and at the right hip. Clinical examination revealed no additional abnormalities. The initial laboratory results showed high calcium (3,5 mmol/L), and normal phosphate (1,07 mmol/L) leve...

Introduction: Approximately 2% of parathyroid adenomas reside in the mediastinum and are not amenable to the traditional cervical approach. Midline full sternotomy has been frequently used to excise these glands but this approach can be associated with significant morbidity. Methods and results: Midline partial sternotomy to the third intercostal space is a valid alternative surgical approach t...

An 81-year-old man was incidentally found to have a posterior mediastinal lesion measuring 25 19 mm behind the trachea and lateral to the esophagus on computed tomography of the chest (Fig 1A, arrow). Parathyroid scintigraphy with Tc-MIBI (technetium with the ligand methoxyisobutylisonitrile) showed persistent focal activity in the posterior mediastinum along the left lateral aspect of the esop...

introduction: radio-guided parathyroid surgery along with other minimally invasive surgeries constitutes the main surgical treatment procedures for different kinds of hyperparathyroidism.  in this article we have reported our experience of radio-guided parathyroid surgery using tc-99m sestamibi. methods: ten patients with hyperparathyroidism included in our study. twenty mci of tc-99m sestamibi...

A 37-year-old Chinese woman was admitted to the First Affiliated Hospital, College of Medicine, Zhejiang University, China in July 2009 with pain in the upper back and hip for 9 months. She denied any chronic medication or illness. Her serum calcium level was 2.73 mmol/L (reference range [RR], 2.082.60 mmol/L), phosphorus 0.68 mmol/L (RR, 0.811.62 mmol/L), alkaline phosphatase 366 IU/L (RR, 30-...

BACKGROUND We report the case of a giant intrathyroidal parathyroid adenoma weighing 59 g in a young woman presenting acutely with severe hypercalcemia requiring correction and adequate preoperative management prior to surgery. Parathyroid adenomas account for 85 % of cases of primary hyperparathyroidism. Those weighing more than 3.5g are classified as giant parathyroid adenomas. There are only...

We report a case of 66-year-old female, who presented with features hypercalcemia and developed acute kidney injury (AKI). Parathyroid hormone level was raised up to 740 pg/ml. Ultrasound sestamibi scan suggested presence right sided parathyroid adenoma. A decision parathyroidectomy taken. The sample that sent for frozen section showed only thyroid tissue. No macroscopically visible or palpable...

An 86-year-old female presented with a two-month history of an enlarging, left-sided jaw mass. The mass persisted after a course of antibiotics prescribed by her dentist. A CT scan of the mandible (Fig. 1) and biopsy from an outside hospital demonstrated characteristics consistent with a benign Giant Cell Tumor. The patient was referred to Head and Neck Surgery for resection. Upon presentation ...