cyclosporine is a selective immunosuppressant that has a variety of applications in medical practice. like phenytoin and the calcium channel blockers, the drug is associated with gingival overgrowth. this review considers the pharmacokinetics, pharmacodynamics, and unwanted effects of cyclosporine, in particular the action of the drug on the gingival tissues. in addition, elucidates the current...

Gingival hyperpigmentation and the condition known as gummy smile are very common dental cosmetic problems. Gingival hyperpigmentation arises due to the excess presence of melanin in certain regions of the gums. In the case of gummy smile, more than the required amount of gingival tissue is exposed upon smiling. An aesthetically pleasing smile should expose only a negligible amount of gingival ...

INTRODUCTION The purposes of this study were to determine the incidence of open gingival embrasures after a single mandibular incisor extraction and to investigate whether age, sex, interproximal pretreatment and posttreatment contact location, or the type of mandibular incisor were predictors of the incidence and magnitude of open gingival embrasures. METHODS Pretreatment and posttreatment i...

Reactive hyperemia reflects a compensatory vasodilation response of the local vasculature in ischemic tissue. The purpose of this study is to clarify the mechanism of regulation of this response in gingival circulation by using pharmacological analysis of reactive hyperemia and histochemical analysis of gingival tissue. Application of pressure to the gingiva was used to create temporary ischemi...

BACKGROUND AND AIMS The anatomical features of gingiva are important in appropriate periodontal treatment planning. This study was designed to determine the anatomic features of gingival in a group of dental students in Tabriz, Iran. MATERIALS AND METHODS One-hundred healthy subjects (aged 20-24 years old) with no history of periodontal or orthodontic treatment and a gingival index of zero or...

Plaque induced gingival enlargement is most commonly seen and when encountered simultaneously with erosive lichen planus poses a challenge to the treating dentist. Prognosis of one condition may influence the prognosis of another condition. The presented case highlights the significance of proper diagnosis and the management of simultaneously occurring gingival lesions. A 49-year-old hypertensi...

Alport Syndrome (AS) is an important hereditary disorder affecting the glomerular basement membrane. Diagnosis of AS is based on the presence of hematuric nephropathy, renal failure, hearing loss, ocular abnormalities and changes in the glomerular basement membrane of the lamina densa. The aims of this case report were to show the changes in the gingival tissues in a patient with AS under thera...

The purpose of this study was to determine the severity of gingival margin discrepancy affecting the mandibular incisors in children with a single-tooth anterior crossbite. The response of the position of the gingival margin to correction of the crossbite also was investigated. Twenty-two subjects with a single central crossbite and 16 subjects with a single lateral crossbite were identified fr...

STATEMENT OF PROBLEM A high percentage of fixed prosthodontic restorations require a subgingival margin placement, which requires the practice of gingival displacement or a deflection procedure to replicate the margins in impression. PURPOSE The purpose of this study was to learn the different gingival displacement techniques that are currently used by dentists in their practice and to compar...

The purpose of this study was to evaluate the inflammatory response in dento-gingival units with or without attached gingiva in monkeys. Two different types of dento-gingival units with or without attached gingiva were established in premolar and first molar areas of three monkeys. In the experimental group, a part of the keratinized gingiva was removed with periodontal scissors following mucop...