نتایج جستجو برای: glanzmanns thrombasthenia

تعداد نتایج: 525  

Journal: :International Journal of Reproduction, Contraception, Obstetrics and Gynecology 2016

Journal: :The Journal of clinical investigation 1977
D R Phillips P P Agin

Platelets from patients with Glanzmann's thrombasthenia have a distinct molecular alteration of the plasma membrane surface, namely decreased amounts of a major glycoprotein designated as IIb (apparent mol wt 142,000). To identify other possible surface defects of thrombasthenic platelets, we labeled the membrane polypeptides of normal and thrombasthenic platelets by two different techniques: l...

Journal: :Blood 1988
P F Nievelstein J J Sixma

Previous studies have indicated that activated blood platelets interact with fibronectin through binding of fibronectin to the glycoprotein IIb-IIIa complex (GPIIb-IIIa). The cell attachment site of fibronectin with its crucial arg-gly-asp(-ser) [RGD(S)]sequence is involved in these bindings. We studied the importance of these interactions for the fibronectin dependence of platelet adhesion und...

Journal: :iranian journal of pediatric hematology and oncology 0
shima kazemzadeh department of laboratory hematology and blood banking, faculty of allied medicine, kerman university of medical sciences rezvan mohammadi pathology and stem cell research center, kerman university of medical sciences, kerman, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (kerman university of medical sciences) fatemeh shadkam farokhi pathology and stem cell research center, kerman university of medical sciences, kerman, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (kerman university of medical sciences) alireza shafiian school of veterinary medicine, shahid bahonar university of kerman, kerman, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (kerman university of medical sciences) mohammad faranoush pediatric growth and development research center, endocrinology institute, iran university of medical science, tehran,سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (kerman university of medical sciences) alireza farsinejad pathology and stem cell research center, kerman university of medical sciences, kerman, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

background: the most common polymorphisms identified in the methylenetetrahydrofolate reductase (mthfr) gene, c677t and a1298c lead to defective activity of this enzyme and increase the risk of venous and arterial thrombosis. there are limited investigations regarding the effects of thrombogenic polymorphisms on the clinical phenotypes of rare hereditary hemorrhagic disorders like glanzmann's t...

Journal: :The Journal of clinical investigation 1980
I Hagen A Nurden O J Bjerrum N O Solum J Caen

Crossed immunoelectrophoresis of Triton X-100 solubilized proteins from normal and abnormal platelets was performed with rabbit antibodies raised against normal platelets. In Bernard-Soulier platelets protein 13 was not detected, and neither the amphiphilic (probably GP Ib) nor the hydrophilic (glycocalicin) glycocalicin-related proteins were seen when monospecific antiglycocalicin antiserum wa...

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