نتایج جستجو برای: gleason grade group
تعداد نتایج: 1123554 فیلتر نتایج به سال:
It was with some surprise that we read of five letters to the Editor [1–5] authored by the Editors of the International Journal of Radiation Oncology Biology Physics, Urology, Urologic Oncology, BJU International, European Urology and the Journal of Urology regarding the recently defined grading system for prostate cancer [6]. For clarification the letter published in the Journal of Urology [1]...
PURPOSE Biopsy Gleason score, serum prostate specific antigen (PSA) levels, and clinical stage are known to be independent predictors of adverse pathological features and biochemical failure after radical prostatectomy. We determine whether various prostate needle biopsy parameters were predictive of either adverse pathological findings or disease recurrence after radical prostatectomy. MATER...
This report presents our experience with T therapy in a cohort of T-deficient men on active surveillance (AS) for Gleason 3 + 3 and Gleason 3 + 4 prostate cancer (PCa). A retrospective chart review identified 28 men with T deficiency who underwent T therapy (T group) for at least 6 months while on AS for PCa. A comparison group of 96 men on AS for PCa with untreated T deficiency (no-T group) wa...
Rapid advances in the discovery of long noncoding RNAs (lncRNAs) have identified lineage- and cancer-specific biomarkers that may be relevant in the clinical management of prostate cancer (PCa). Here we assembled and analyzed a large RNA-seq dataset, from 585 patient samples, including benign prostate tissue and both localized and metastatic PCa to discover and validate differentially expressed...
Background: Prostate cancer has a propensity to invade and grow along nerves, a phenomenon called perineural invasion (PNI). Recent studies suggest that the presence of PNI in prostate cancer has been associated with cancer aggressiveness.Methods: We investigated the association between PNI and lethal prostate cancer in untreated and treated prostate cancer cohorts: the Swedish Watchful Waiting...
Radical prostatectomy (RP) specimens with unfavorable pathol‐ ogy increased over nine years, but the reasons remain unclear, according to a study reported at the American Urological Asso‐ cia on (AUA) 2016 Annual Mee ng. Results were reported by Katherine Rotker, MD, of Brown University in Providence, RI. Following US Preven ve Health Services Task Force (USPSTF) 2009 and 2012 recommenda ons ag...
Prior studies of radical prostatectomies have reported a small percentage of men with biochemical progression after radical prostatectomy showing organ-confined, Gleason Score 6. One might predict that this should virtually never occur. We identified 2551 (1983-2005) radical prostatectomies coded by the urologists at our institution as pathologically organ-confined, Gleason score 6 cancer with ...
Background: Prostate cancer is one the most common malignancy in men worldwide, and acinar adenocarcinoma prevalent one. Gleason score grade group recently used to predict therapy prognosis based on pattern. Her-2 Ki-67 are markers that widely studied breast cancer, but their role prostate still unclear. a transmembrane protein involved oncogenesis. We hope by using basic determinant pattern an...
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