BACKGROUND Four previously reported studies have tested for association of blood proteins with neocortical amyloid-β burden (NAB). If shown to be robust, these proteins could have utility as a blood test for enrichment in clinical trials of Alzheimer's disease (AD) therapeutics. OBJECTIVE This study aimed to investigate whether previously identified blood proteins also show evidence for assoc...

Introduction: Glioblastoma is an aggressive malignancy of human brain with poorly understood pathogenesis. Voltage-gated potassium (Kv) channels and Matrix metalloproteinases (MMPs) are highly expressed in malignant tumors and involved in the progression and metastasis of glioblastoma. The purpose of this study was to determine whether a voltage-dependent potassium channel blocker could modulat...

The UAIC-RoDia-DepTb is a balanced treebank, containing texts in non-standard language: 2,575 chats sentences, old Romanian texts (a Gospel printed in 1648, a codex of laws printed in 1818, a novel written in 1910), regional popular poetry, legal texts, Romanian and foreign fiction, quotations. The proportions are comparable; each of these types of texts is represented by subsets of at least 1,...

Searching for information on the web is hard; the user may not know what they are looking for, they may refine their search from information gathered by preliminary naive searches, and they may be looking for luminous sites that have many external links so that they can browse further. Information visualization can aid the user in many of these search related tasks. Certainly, the user is famil...

Object manipulation is a basic element in everyday human lives. Robotic manipulation has progressed from maneuvering single-rigid-body objects with firm grasping to maneuvering soft objects and handling contact-rich actions. Meanwhile, technologies such as robot learning from demonstration have enabled humans to intuitively train robots. This paper discusses a new level of robotic learning-base...

Glioblastoma multiform(GBM) is the most prevalent primary brain tumor. Exosomes are extracellular vehicles for exchanging information between various cell types including cancer and normal cells. Exosomes are indicative of pathophysiological conditions of brain tumors that could be used in diagnosis and prognosis of GBM. In tumors, exosomes could carry various molecules like several miRNAs and ...

A woman of 18 presented with a supraventricular tachycardia, subsequently shown to be caused by atrioventricular nodal reentry, which abruptly deteriorated to a multiform ventricular tachycardia. She had not received any antiarrhythmic drugs nor did she have any of the disorders that are usually associated with this atypical ventricular tachycardia.