نتایج جستجو برای: glipizide

تعداد نتایج: 326  

Journal: :Molecules 2012
Virginia D Kappel Danielle F Pereira Luisa H Cazarolli Samantha M Guesser Carlos H Blum da Silva Eloir P Schenkel Flávio H Reginatto Fátima R M B Silva

In this study, the in vivo effect of the crude extract and n-butanol and aqueous residual fractions of Baccharis articulata (Lam.) Pers. on serum glucose levels, insulin secretion and liver and muscle glycogen content, as well as in vitro action on serum intestinal disaccharidase activity and albumin glycation were investigated. Oral administration of the extract and fractions reduced glycemia ...

Journal: :The Journal of clinical investigation 1988
B S Kuo G Korner T D Bjornsson

The effects of sulfonylureas on the production of plasminogen activator (PA) and antiactivator (PAI) were investigated using bovine aortic endothelial cells. All compounds studied stimulated PA release (1.3- to 5.2-fold), with glipizide being the most potent, followed by tolazamide, chlorpropamide, and tolbutamide, in that order, while glyburide was the least effective. Both tissue-type and uro...

2014

CAM [12]. The patients under multiple systems of medication may have concerns about the possibility of the occurrence of polypharmacosis, thereby resulting in the interaction between drug molecules. The interactions may be apprehended and analyzed to be of drug-drug, herb-drug or food-drug varieties. In case of Drug-Drug Interactions the reaction mode is either pharmacodynamics or pharmacokinet...

Journal: :The Journal of biological chemistry 1987
H Schmid-Antomarchi J De Weille M Fosset M Lazdunski

Sulfonylureas are powerful hypoglycemic drugs that have been used for decades to treat diabetic patients. This paper describes a 86Rb+ flux technique that permits one to study easily the properties of ATP-modulated K+ channels in RINm5F insulinoma cells. Sulfonylureas inhibit this type of K+ channel under conditions of intracellular ATP depletion. The most potent sulfonylureas (glibenclamide, g...

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