نتایج جستجو برای: glycoprotein b
تعداد نتایج: 977663 فیلتر نتایج به سال:
Herpesviruses are ancient pathogens that infect all vertebrates. The most conserved component of their entry machinery is glycoprotein B (gB), yet how gB functions is unclear. A striking feature of the murid herpesvirus 4 (MuHV-4) gB is its resistance to neutralization. Here, we show by direct visualization of infected cells that the MuHV-4 gB changes its conformation between extracellular viri...
We thank David A. Stevens et al. (1) for the letter suggesting different results regarding the effect of P-glycoprotein on the brain concentration of amphotericin B (AMB) by P-glycoprotein knockout mice. In contrast to our finding that blockage of P-glycoprotein with inhibitors enhances the brain uptake of AMB (2), they found that brain AMB concentrations were significantly lower in Mdr1a/1b / ...
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