Methods The present study involved the synthesis of gold nanoparticles using a sodium cholate, as both reducing and capping agent and characterization by UVVisible spectroscopy and High ResolutionTransmission Electron Microscopy (HRTEM). The antibacterial activity on significant bacterial species was evaluated by micro broth dilution method. The mechanism for antibacterial action of the gold na...

Z. Naturforsch. 51 b, 1067-1071 (1996); received March 8, 1996 Myochrysin, Auranotin. Gold(I) Complexes, Photochemistry, Luminescence Myochrysin (sodium aurothiomalate hydrate) and auranofin [2,3.4,6-tetra-O-acetyl-l-thio-ßD-glucopyranosato-S)(triethylphospine)gold(I)] are luminescent in the solid state and in ethanol glasses at 77 K (myochrysin: Amax = 600 nm; auranofin: 618 nm). Aqueous myoch...

A trial of sodium aurothiomalate as an antiproteinase drug in the treatment of murine muscular dystrophy is reported. A blind controlled comparison of high (25 microgram/10 g body weight) and low dose gold (5 microgram/10 g body weight) with saline-injected control animals was made, all injections being given three times weekly. The body weights and functional ability of the mice were assessed ...

Reactions of the complexes bisethylendiammine gold(III) and bisethylendiammine platinum(II) with calfthymus DNA were comparatively analysed. Both complexes bind DNA non-covalently most probably on the basis of electrostatic interactions. Binding of either complex at low ratios results into modest modifications of B-type DNA conformations, as detected by CD. Far larger CD alterations are observe...

Background Colonoscopy is the gold standard investigation for assessing of the intra-luminal colorectal pathology. Effective bowel preparation contributed efficient visualizing of the colon. Osmotic laxatives such as sodium phosphate (NaP) are commonly used for colonic preparation for colonoscopy. A meta-analysis suggested that NaP offered a more effective and more readily completed preparation...

“If you have always done it that way, it is probably wrong.” —Charles F. Kettering, 1876–1958 The morbidity of decompensated heart failure is due to volume overload, a consequence of increased total body sodium.1,2 Failure to adequately reduce total body sodium contributes to progressive ventricular dysfunction, worsening heart failure, and excess morbidity. Ultrafiltration is the gold standard...

A supported gold nanoparticle-catalyzed strategy has been utilized to promote a click chemistry reaction for the synthesis of 1,2,3-triazoles via azide-alkyne cycloaddition (AAC) reaction. While advent effective non-copper catalysts (i.e., Ru, Ag, Ir) demonstrated catalysis AAC reaction, additional robust catalytic systems complementary copper catalyzed remain in high demand. Herein, Au nanopar...

Life-table analysis was applied to the records of 317 patients with rheumatoid arthritis (RA) treated with sulphasalazine (SAS), 201 treated with sodium aurothiomalate (gold), and 163 with penicillamine. They comprised all those treated in our department with these drugs between January 1973 and July 1984. Risks of treatment termination for all reasons were similar for each drug at five years (...

The remarkable effect of an unsupported nanoporous gold catalyst (AuNPore) on chemoselective hydrogenation of α,β-unsaturated aldehydes using silane has been described. Enals can be reduced with excellent selectivity, giving the corresponding allylic alcohols in good to high chemical yields.