BACKGROUND Activated leukocyte cell adhesion molecules (ALCAMs) play an essential role in tumor metastasis and are higher in some patients with breast cancer. AIM This study aimed to evaluate ALCAM as an early diagnostic biomarker for breast cancer and how it compares with other markers. SUBJECTS AND METHODS One-hundred and sixty-one women were selected for this study. They were divided int...

Children's depressive symptoms in the transition from preschool to school are rarely investigated. We therefore tested whether children's temperament (effortful control and negative affect), social skills, child psychopathology, environmental stressors (life events), parental accuracy of predicting their child's emotion understanding (parental accuracy), parental emotional availability, and par...

OBJECTIVES To determine the development rate of hepatocellular carcinoma and survival of patients diagnosed to have regenerative, and low-grade and high-grade dysplastic liver nodules. DESIGN Retrospective descriptive study. SETTING Acute public hospital, Hong Kong. PATIENTS Patients with non-malignant liver nodules confirmed by imaging-guided liver biopsy between January 1997 and Decembe...

PURPOSE The molecular pathogenesis of uveal melanoma is poorly understood but is usually accompanied by amplification of chromosome 8q, suggesting the activation of one or more oncogenes. We recently identified a gene expression profile that distinguishes low-grade from high-grade melanomas. In this profile, a cluster of genes at chromosome 8q was overexpressed in high-grade tumors, providing a...

BACKGROUND Surgical hip dislocation enables complete exposure of the hip joint for treatment of various hip disorders.There is limited information regarding the complications associated with this procedure. Our purpose is to report the incidence of complications associated with surgical dislocation of the hip in a large, multicenter patient cohort. METHODS A retrospective, multicenter analysi...

This longitudinal study examined how depressive symptoms relate to children's self-perceptions and to estimates of children's cognitive distortions about the self in a nonclinical sample of children who were followed from 4th grade (n = 248) through 6th grade (n = 227). Report card grades measured children's academic competence, and teachers' ratings of children's level of peer acceptance at sc...

BACKGROUND AND OBJECTIVE. There is a need for objective semiquantitative indexes for the evaluation of results of single-photon emission tomography (SPECT) in patients with brain glioma. The aim of this study was to validate the total size index (TSI) and total intensity index (TII) based on technetium-99m-methoxyisobutylisonitrile ((99m)Tc-MIBI) SPECT scans to discriminate the patients with hi...

We determined whether a widely used assessment of visual-motor skills, the Beery-Buktenica Developmental Test of Visual-Motor Integration (VMI), is appropriate for use as an outcome measure for handwriting interventions. A two-group pretest-posttest design was used with 207 kindergarten, first-grade, and second-grade students. Two well-established handwriting measures and the VMI were administe...

OBJECTIVES To show that lipid and lipoprotein levels and cell sodium and potassium content and transport could change depending on the degree of hypertension. DESIGN AND METHODS Forty-three hypertensive patients and 20 healthy subjects were recruited at the Cardiology and Biochemistry Departments of Tlemcen University Hospital Centre (Northwest of Algeria). RESULTS Levels of CHOL, TG, PL, H...

Columnar cell change in breast epithelium is frequently encountered in biopsies performed for evaluation of radiographically detected microcalcifications. While columnar cell change by itself is typically of no clinical consequence, on occasion cytologic atypia may be present, a finding now termed “flat epithelial atypia (FEA)”. Morphologic, immunophenotypic, and genetic associations between FE...