Sustainable food production is one of the main goals of the modern world. Nowadays, there is a growing interest in the exploitation of the by-products generated from agriculture and food production as raw materials for obtaining high-value products, which can be used for various purposes in the pharmaceutical, cosmetics and food industries. During the winemaking process, about 20 % of the grape...

Chronic inflammatory bowel disease is characterised by an up-regulation of the synthesis and release of a variety of pro-inflammatory mediators leading to excessive tissue injury. Flavonoids are able to inhibit enzymes and/or due to their antioxidant properties regulate the immune response. The goal of the present study was to evaluate the mechanisms of action of phenolic compounds present in g...

Grape is one of the most popular and widely cultivated fruits in the world. Although grape skin and seeds are waste product of the winery and grape juice industry, these wastes contain large amounts of phytochemicals such as flavonoids, phenolic acids, and anthocyanidins, which play an important role as chemopreventive and anticancer agents. We evaluated efficacies of grape skin and seeds on he...

In this paper we describe the current status of the GRAPE-6 project to develop a special-purpose computer with a peak speed exceeding 100 T ops for the simulation of astrophysical N -body problems. One of the main targets of the GRAPE-6 project is the simulation of dense stellar systems. In this paper, therefore, we overview the basic algorithms we use for the simulation of dense stellar system...

Polyphenol-rich grape seeds have a beneficial effect on human health. The present study was performed to investigate the effects of grape seeds on antioxidant activities in rats. Male Sprague-Dawley rats were randomly divided into a control diet group (C), a high-fat diet group (HF), a 5% grape seed-supplemented control diet group (G), and a 5% grape seed-supplemented high-fat diet group (HG). ...

Pre-embryogenic calli were obtained from the culture of fertilized immature ovules of muscadine ( Vitis rotundifolia Michx.) and seedless bunch grapes ( Vitis vinifera L.) on: 1) Murashige & Turcker (MT, 1969) basal medium supplemented with 4.4 μM 2, 4-D (2, 4-dichlorophenoxyacetic acid) and 1 μM BA (6-benzyladenine) with 6.0% (w/v) sucrose; 2) Chee and Pool (CP, 1978) basal medium supplemented...