Congenital combined pituitary hormone deficiency (CPHD) is associated with deficiencies of anterior pituitary hormones. PROP1 gene mutations are often responsible for CPHD, but few such cases have been reported in Japan. This study describes a 37-year-old Japanese man with CPHD, treated with hydrocortisone, testosterone, and L-thyroxine, who was evaluated for adult growth hormone deficiency (GH...

the ovine melatonin receptor 1a (mtnr1a) and aromatase (cyp19) genes were structurally characterized and the association between their variants and reproductive and growth traits was studied in kurdi sheep at kurdi sheep breeding station located in shirvan, iran. the genomic dna was extracted by guanidine thiocyanate-silica gel method. polymerase chain reaction was carried out to amplify 824 bp...

Bovine ghrelin, a 27 amino acid peptide, has been identified in oxyntic glands of the abomasum. It is an endogenous ligand for growth hormone secretagogue receptor and stimulates food intake and growth hormone secretion. The bovine GHRL gene was completely sequenced and consists of five exons and four introns. Like mouse and human GHRL genes, we found that the bovine GHRL gene also contains a f...

Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone. Identification of a novel 17,000-Dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercal-cemia of malignancy. Synthetic human parathyroid hormone-like protein stimulates bone resorp-tion and causes hypercalcemi...

prophet of pou1f1 (prop1) plays direct or indirect important roles in the morphogenesis of pituitary gonadotropes as well as lactotropes, somatotropes and caudomedial thyrotropes. it also controls the expression of growth hormone, prolactin and thyrotropin subunits through regulatory pit1 factor. these hormones have important influences on production traits in most animal species including the ...

Rhamdia quelen is an important Neotropical catfish species for fisheries and aquaculture in southern Brazil, where it is called Jandia. Like other native Brazilian species of economic importance, R. quelen genetics needs more attention for animal breeding programs. The growth hormone gene is known to be linked to a number of molecular markers and quantitative trait loci. We sequenced the coding...