Background: Methotrexate (MTX) is one of the frequently used chemotherapeutic agents, especially in hematological malignancies and solid tumors. Objectives: MTX hepatotoxicity symptoms range from elevations in serum aminotransferases to hepatocyte necrosis and fibrosis. The time of medication administration significantly impacts treatment outcomes. Hence this study evaluated the protective eff...

‎Suppose $n$ is a fixed positive integer‎. ‎We introduce the relative n-th non-commuting graph $Gamma^{n} _{H,G}$‎, ‎associated to the non-abelian subgroup $H$ of group $G$‎. ‎The vertex set is $Gsetminus C^n_{H,G}$ in which $C^n_{H,G} = {xin G‎ : ‎[x,y^{n}]=1 mbox{~and~} [x^{n},y]=1mbox{~for~all~} yin H}$‎. ‎Moreover‎, ‎${x,y}$ is an edge if $x$ or $y$ belong to $H$ and $xy^{n}eq y^{n}x$ or $x...

In the current study, the effects of ethanol (EtOH) on toxicokinetics of methamphetamine (MA) and its metabolite amphetamine (AP) were investigated. A single dose of MA hydrochloride at 15 mg/Kg was given intragastrically, either alone (MA group; n = 8) or in conjunction with 3 g/Kg EtOH (MA+EtOH group; n = 8) to rabbits. In placebo group, normal saline only was given (placebo group; n = 4). Pl...

In the current study, the effects of ethanol (EtOH) on toxicokinetics of methamphetamine (MA) and its metabolite amphetamine (AP) were investigated. A single dose of MA hydrochloride at 15 mg/Kg was given intragastrically, either alone (MA group; n = 8) or in conjunction with 3 g/Kg EtOH (MA+EtOH group; n = 8) to rabbits. In placebo group, normal saline only was given (placebo group; n = 4). Pl...

conclusions bacterial infection has been suggested in the pathogenesis of both ss and cs. in addition, h. pylori is a resident of the oral cavity, thus may be involved in the development and progression of these lesions. hence, search for h. pylori antibody in blood of patients with ss is suggested. background sjogren’s syndrome (ss) is a chronic autoimmune disease characterized by lymphocytic ...

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