The hair follicle is a mini-organ, consisting of many different types and groups of cells, capable of frequent remodeling and cycles of growth. Immune privilege (IP) is believed to exist in the anagen growth stage of the hair follicle (HF). Previous studies using immunohistology have illustrated unique downregulation of major histocompatibility complex Class I in the HF bulb, as well as express...

cartilage hair hypoplasia (chh), is a rare cause of metaphyseal chondrodysplasia and short stature. other features included hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (hirschsprung disease, celiac, …) and increased risk of cancer. the disease is an autosomal recessive disorder and previously has not been reported in iran. we report a 9-year-old boy diagnosed as carti...

The temporal response of auditory-nerve (AN) fibers to a steady-state vowel is investigated using a computational auditory-periphery model. The model predictions are validated against a wide range of physiological data for both normal and impaired fibers in cats. The model incorporates two parallel filter paths, component 1 (C1) and component 2 (C2), which correspond to the active and passive m...

kawasaki disease is a multi system disorder with varying clinical expressions. this disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. we describe an unusual instance of hair loss in a patient with kawasaki disease. a 26 months old boy developed prolonged high fever, bilat...

manganese and cobalt concentrations in hair and nail were determined by flame atomic absorption spectrophotometer (aas).the mean manganese in hair and nail were 0.54 â± 0.35mg/g and 0.68 â± 0.30mg/g while the mean cobalt in hair and nail were 0.30 â± 0.24mg/g and 0.460.37mg/g respectively. a progressive increase in cobalt concentrations in hair and nails with age indicated no significant differ...

It is often assumed that at frequencies in the tuning-curve tail there is a passive, constant coupling of basilar-membrane motion to inner hair cell (IHC) stereocilia. This paper shows changes in the phase of auditory-nerve-fiber (ANF) responses to tail-frequency tones and calls into question whether basilar-membrane-to-IHC coupling is constant. In cat ANFs with characteristic frequencies > or ...

Twenty Naieni breed replacement ewe lambs were used to determine the substitution effects of treated wheat straw with exogenous fiber-degrading enzymes for alfalfa hay on wool characteristics. Five treatment diets were included: 1) control (100% alfalfa hay without wheat straw), 2) 10% enzyme treated wheat straw replaced for alfalfa hay, 3) 20% enzyme treated wheat straw replaced for alfalfa ha...

PURPOSE OF REVIEW This review covers the articles published between 2010 and early 2011 that presented new findings on inner-ear efferents and their ability to modulate hair cell function. RECENT FINDINGS Studies published within the review period have increased our understanding of efferent mechanisms on hair cells in the cochlear and vestibular sensory epithelium and provide insights on eff...

There is growing evidence that the dynamics of biological systems that appear to be exponential over short time courses are in some cases better described over the long-term by power-law dynamics. A model of rate adaptation at the synapse between inner hair cells and auditory-nerve (AN) fibers that includes both exponential and power-law dynamics is presented here. Exponentially adapting compon...