kawasaki disease is a multi system disorder with varying clinical expressions. this disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. we describe an unusual instance of hair loss in a patient with kawasaki disease. a 26 months old boy developed prolonged high fever, bilat...

Background: Smoking is the most common and cheapest addictive substance and has physical, psychological, and social side effects. Personality traits and low self-control have been identified as key factors for substance and tobacco abuse. This study examined the relationship between personality traits and self-control, and symptoms of nicotine dependence in male prisoners. Methods: This was a d...

BACKGROUND Nicotiana attenuata is attacked by larvae of both specialist (Manduca sexta) and generalist (Spodoptera exigua) lepidopteran herbivores in its native habitat. Nicotine is one of N. attenuata's important defenses. M. sexta is highly nicotine tolerant; whether cytochrome P450 (CYP)-mediated oxidative detoxification and/or rapid excretion is responsible for its exceptional tolerance rem...

objectives: according to the gateway drug theory, tobacco use is a predisposing factor for future substance abuse. this study was conducted to compare nicotine and opiate dependents to identify the differences between their personality traits and psychopathology that makes them turn to other substances after cigarette smoking. methods: a causal-comparative study was conducted. three groups were...

ôbjective: previous studies reported that individuals with parkinson’s disease are less likely to have smoking history and it seems that nicotine has a neuroprotective effect. the authors have conducted a case-control retrospective study to determine if there is an association between cigarette smoking and parkinson’s disease. methods: ïn a matched case-control study, 92 individuals with parkin...

manganese and cobalt concentrations in hair and nail were determined by flame atomic absorption spectrophotometer (aas).the mean manganese in hair and nail were 0.54 â± 0.35mg/g and 0.68 â± 0.30mg/g while the mean cobalt in hair and nail were 0.30 â± 0.24mg/g and 0.460.37mg/g respectively. a progressive increase in cobalt concentrations in hair and nails with age indicated no significant differ...

Each CYP2A6 gene variant metabolizes nicotine differently depending on its enzymatic activities. The normal nicotine metabolizer CYP2A6(*)1A is associated with high scores of nicotine dependence (5-10) on the Fagerström Test for Nicotine Dependence (FTND) scale because it encodes for enzymes that catalyze nicotine 100%. Slow nicotine metabolizers (i.e., CYP2A6(*)1H, CYP2A6(*)4A, CYP2A6(*)9, and...

nicotine is one the chemical substance with high level of toxically. it crosses the placenta and accumulates in the developing organs of fetus. our previous investigations indicated that collagen type iv plays a key role in basement membrane of various embryonic organs. in this study we evaluated the effect of maternal nicotine exposure pre and postnatal period on collagen iv expression during ...