BACKGROUND To investigate the controlling efficacy of ondasetron and haloperidol in regard to the postcardiotomy delirium. METHODS We included in this prospective, randomized, double-blinded study 80 patients who developed delirium after heart surgery with the application of heart lung-machine. The patients were divided into two, equally-sized groups, which on detection of delirium received o...

Administration of haloperidol, a common neuroleptic, to pregnant or lactating rats impaired the masculine sex behavior of their male offspring. Prenatal haloperidol did not affect testosterone concentrations in fetuses. Maternal administration of apomorphine, a dopamine agonist, and of alpha-methyl-p-tyrosine, an inhibitor of dopamine synthesis, also demasculinized male offspring. In both exper...

objective: sexual dysfunction in patients who take antipsychotics causes adecline in their quality of life and medication acceptance. considering the restrictions in cross sectional design of many earlier researches, we used a clinical trial aimed at assessing sexual dysfunction by substituting risperidone, an atypical antipsychotic drug, with haloperidol, a typical one . method: this clinical ...

References 1. AlMadhyan AB. Angioedema associated with haloperidol. Int J Health Sci (Qassim) 2015;9:76-8. 2. Kahlon S, Lee C, Chirurgi R, Worku Hassen G. Angioneurotic edema associated with haloperidol. Case Rep Emerg Med 2012;2012:725461. 3. Corke PJ, Murray G. Angio-oedema with droperidol. Anaesth Intensive Care 1993;21:375. 4. Muzyk AJ, Cvelich RG, Kincaid BR, Preud’homme XA. Angioedema occ...

Effects of intrastriatal injections of haloperidol (Dopamine antagonist) and D-amphetamine (Dopamine agonist) on lordosis behaviour were studied in ovariectomized female albino rats, after priming with subcutaneous injections of estrogen and progesterone. The lordosis quotient (LQ) significantly increased after haloperidol, and decreased following D-amphetamine treatment. However, the inhibitor...

Monkeys trained in either one-trial recognition at 8- to 10-min delays or multi-trial discrimination habits with 24-h intertrial intervals received systemic cholinergic and dopaminergic antagonists, scopolamine and haloperidol, respectively, in separate sessions. Recognition memory was impaired markedly by scopolamine but not at all by haloperidol, whereas habit formation was impaired markedly ...

90 schizophrenic patients in three regimes of thirty patients each, were treated for a period of three weeks with haloperidol alone, E.C.T. alone and E.C.T. + haloperidol in combination respectively. Rating them on R. P. scale (Rockland and Pollin, 196a) & Disability Rating Scale (Gautam, 76) showed that the E.C.T. + haloperidol receiving group was significantly better on several measures on da...