Introduction: Almost all malignant tumors have the potential to eventually produce bone metastasis. The aim of the current study was to report the distribution pattern and imaging characteristics of bone metastases detected by conventional whole body bone scintigraphy in patients with different types of malignancies and to assess their relationship with the complain...

background and objective: sensory neurons have critical role in improvement of functional outcome of any neuroprotective strategy. the herbal medicine nepeta menthoides has been reported to have anti-apoptotic effect on axotomized spinal motoneurons. in the present study, the putative neuroprotective effect of nepeta menthoides on the axotomized dorsal root ganglion sensory neurons in neonate r...

Introduction: Diagnosis of lesions and bone defects is very important and there is a lack of substantial studies on the most appropriate method for bone defect measurement. Hence, the aim of this study is to evaluate the accuracy of multi-slice computed tomography (MSCT) and cone-beam computed tomography (CBCT) in the diagnosis of mandibular bone defects present in sheep. Material & Methods: T...

PURPOSE The quantitative measurements of hand bones, including volume, surface, orientation, and position are essential in investigating hand kinematics. Moreover, within the measurement stage, bone segmentation is the most important step due to its certain influences on measuring accuracy. Since hand bones are small and tubular in shape, magnetic resonance (MR) imaging is prone to artifacts su...

A s anyone who has taken a photograph with shaky hands can attest, camera movement creates image blur. Because photosensors must integrate over a finite interval to acquire a noise-free image, any motion that occurs during that interval will blur over the spatial details of an object by the amount of space traversed (Fig. 1). This simple fact creates headaches for engineers designing scientific...

The purpose of this study was to clarify clinical and radiographic features of bone changes associated with soft-tissue tumors of the hand. We reviewed clinical records and radiographs of 115 patients who had undergone operations for soft-tissue tumors or tumorous conditions of the hand. Bone changes were detected in the radiographs of 21 of the 115 patients. Giant cell tumor of tendon sheath w...

Background: No scientific evidence exists regarding the amount of bone cement used and discarded in primarycemented Total knee arthroplasty (TKA). The aim of this study was to identify the exact amount of bone cement utilizedfor component fixation in primary TKA.Methods: In a prospective study carried out at five centers, 133 primary cemented TKAs were performed. One packof 40g Palacos bone cem...

PURPOSE To investigate the effects of music therapy on the pain behaviors and survival of rats with bone cancer pain and analyze the mediating mechanism of mitogen activated protein kinase (MAPK) signal transduction pathway. METHODS Male Wistar rats aged 5-8 weeks and weighing 160-200 g were collected. The rat models of colorectal cancer bone cancer pain was successfully established. Animals ...

Objective Cancer-induced bone pain is a common clinical problem in breast cancer patients with bone metastasis. However, the mechanisms driving cancer-induced bone pain are poorly known. Recent studies show that a novel protease, asparaginyl endopeptidase (AEP) plays crucial roles in breast cancer metastasis and progression. We aim to determine the functions and targeted suppress of AEP in a mo...