Alkalinization of normally acidic intracellular compartments or acidification of a mildly alkaline cytoplasm by biochemical or genetic manipulation has been demonstrated to inhibit both endocytosis and secretion (Tartakoff, 1983a; Cosson et al., 1989; Mellman et al., 1986; Davoust et al., 1987; Cosson et al., 1989; van Deurs et al., 1989; Maxfield & Yamashiro, 1991; Hansen et al., 1993). These ...

The interobserver variability and the ability of the Lauge-Hansen, A.O. and Broos-Bisschop classification systems to encompass all the ankle fracture patterns were investigated in a study of the radiographs of 293 patients with a total of 294 malleolar fractures. Three different orthopaedic surgeons independently evaluated the sets of ankle radiographs. The examiners classified the ankle fractu...

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INTRODUCTION Paenibacillus larvae larvae (WHITE) is the causative agent of American foulbrood (AFB) in honey bees (Apis mellifera L.). This disease is lethal to honey bee colonies if curative control actions are not taken (HANSEN and BRØDSGAARD, 1997). Recently, increasing problems with AFB in Europe (DROBNÍKOVÁ,1992; HANSEN,1996; OTTEN, 1991; VON DER OHE et al. 1996) have renewed the interest ...