نتایج جستجو برای: hantzsch synthesis
تعداد نتایج: 409399 فیلتر نتایج به سال:
hantzsch 1 ,4- dihy&opyridines; are rapidly oxidized to the corresponding pyridine derivatives using zinc chlorochromate nonahydrate [zn(c1cro ) .9h o] in dichloromethane at room temperature. in addition to aromatization, no loss of the 4- substituent is observed
A new series of 2-hydrazone-thiazoline-4-ones 3a-d and 2-hydrazone-5arylidene-thiazoline-4-ones 4a-h, 5a-f and 6a-b were synthesized starting from various thiosemicarbazones by the Hantzsch condensation with chloroacetic acid. The newly synthesized compounds were screened for their antimicrobial activity against 4 strains of bacteria: Staphylococcus aureus (ATCC 29213), Bacillus subtilis (ATCC ...
New and known arylidene-hydrazinyl-thiazole derivatives have been synthesized by a convenient Hantzsch condensation. All compounds were evaluated for their in vitro cytotoxicity on two carcinoma cell lines, MDA-MB231 and HeLa. Significant antiproliferative activity for 2-(2-benzyliden-hydrazinyl)-4-methylthiazole on both MDA-MB-231 (IC50: 3.92 µg/mL) and HeLa (IC50: 11.4 µg/mL) cell lines, and ...
We have developed a direct amine/acid-catalyzed stereoselective hydrogenation of a variety of Wieland-Miescher (W-M) ketones, Hajos-Parrish (H-P) ketones and their analogs with organic hydrides (Hantzsch esters) as the hydrogen source. This astonishingly simple and biomimetic approach was used to construct highly functionalized chiral bicyclo[4.4.0]decane-1,6-diones in a diastereoselective fash...
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