Haptoglobin levels are measured in systematic lupus erythematosus patients as part of the workup for anemia, with low levels indicating hemolysis. Haptoglobin is an acute phase protein. We present 2 lupus patients who were found to have low haptoglobin levels in the absence of other evidence of hemolysis.

BACKGROUND Allergic rhinitis (AR) is an allergic disorder of the nasal tissue that underlies diseases such as sinusitis, otits and asthma. Different predisposing factors including immunological and non-immunological factors contribute to the disease pathogenesis. OBJECTIVE To investigate association of haptoglobin (Hp) phenotypes (Hp1-1, 2-1 and 2-2) with serum immunoglobulins A and E levels ...

Improved diagnosis of psoriasis, by new biomarkers, is required for evaluating the progression rate of the disease and the response to treatment. Haptoglobin (Hpt), a glycoprotein secreted by hepatocytes and other types of cells including keratinocytes, was found with glycan changes in psoriasis and other diseases. We previously reported that Hpt isolated from plasma of psoriatic patients is mo...

Health degradation modifies Trp metabolism through induction of Trp catabolism. This could limit the amount of Trp available for growth. The aims of the present experiment were to investigate the effects of a low grade inflammation and dietary Trp on growth and Trp metabolism. Eighty weaned pigs were assigned to 4 experimental treatments according to a 2 x 2 factorial arrangement: 2 sanitary st...

hemolysis in patients exhibiting a concurrent acute-phase reaction as indicated by increases in C-reactive protein. The sensitivity of haptoglobin at a cutoff of 250 mgfL, however, is somewhat less than in situations where only hemolysis is present (2). Nonetheless, it is apparent that the decline in serum haptoglobin concentrations, owing to its complexing with hemoglobin and eventual removal ...

The objective of this study was to evaluate, over 2 consecutive years, the effects of acclimation to human interaction on performance, temperament, plasma concentrations of hormones and metabolites, and pregnancy rates of Brahman-crossbred cows. A total of 160 Braford and 235 Brahman x British cows were assigned to the 2-yr study. Approximately 45 d after weaning (August 2006) in yr 1, cows wer...

Phenotype distributions of some genetic polymorphisms are reported in a sample of 721 diabetics and 515 non-diabetic, non-blood donor controls. Reference is also made, in the case of the ABO and Rhesus systems, to previously published results for blood donors resident in the Durham area. Non-insulin-taking diabetics show an increased frequency of blood group A1 (and A1 + A2) when compared with ...

The concentration of haptoglobin in sera of healthy women and patients with non-malignant and malignant ovarian tumours was measured by two methods, i.e. complex formation with haemoglobin and complex formation with concanavalin A. High correlation (r = 0.74) between both the methods was found in the group of healthy women, but correlation coefficients were much lower in the group of non-malign...

Abraham (1) and Schutt (2), employing the method of continuous polyacrylamide electrophoresis for the sepa^ ration of serum proteins, found abnormal variations of haptoglobin levels together with those of transferrin (these proteins being a2and j3-globulins respectively), which gave a good indication for an early diagnosis of bronchial neoplasms. These authors reported (1,2) that in patients wi...

Materials and methods: Forty finishing pigs were used in a 12-day disease challenge study. Dietary treatments included no DFM (Control; 20 pigs), DFM provided in drinking water (E faecium), or DFM provided in feed (Bacillus). Ten Control pigs were not challenged with Salmonella Typhimurium; the remaining 30 pigs were inoculated on Day 0. Fecal samples were cultured for Salmonella Typhimurium on...