The study is aimed at development of physicochemical parameters and to investigate the active principle present in Tridax procumbens Linn. Tridax procumbens Linn. (Asteraceae) commonly known as Coat Buttons is an important plant used against various disorders in indigenous system of medicine such as Wound-Healing, Hepatoprotective, Anti-Inflammatory, Anti-diabetic and Immunomodulatory activitie...

Dry leaf extracts of eastern teaberry (Gaultheria procumbens L.) were evaluated as a source of bioactive phytocompounds through systematic activity testing and phytochemical profiling. The antioxidant efficiency was tested using five complementary in vitro models (DPPH; FRAP; linoleic acid (LA) peroxidation assay; O2•- and H2O2 scavenging tests) in parallel with standard antioxidants. The 75% m...

BACKGROUND Launaea procumbens (L.) is traditionally used in the treatment of various human ailments including pulmonary damages. The present study was arranged to evaluate the role of Launaea procumbens methanol extract (LME) against carbon tetrachloride (CCl4) induced oxidative pulmonary damages in rat. METHODS 36 Sprague-Dawley male rats (170-180 g) were randomly divided into 06 groups. Aft...

In this study, the effects of an aqueous extract of the leaves of Tridax procumbens on the haematology, plasma biochemistry and ocular indices of oxidative stress was investigated in alloxan induced diabetic rats. Diabetes mellitus was induced by injection of alloxan (80 mg/kg body weight), via the tail vein. The extract was administered orally at 100, 200 and 300 mg/kg (both to normal and diab...

BACKGROUND Microbial infections and resulting inflammation and oxidative stress are common pathogenesis of gastrointestinal tract (GIT) disorders. In South Africa, several species of the genus Maytenus are used in traditional medicine to treat various infectious diseases. Most of the previous work on this genus was focused on nonpolar extracts from the root and bark. In this study, leaf extract...

BACKGROUND Low-back pain (LBP) is a common condition and imposes a substantial economic burden upon people living in industrialized societies. A large proportion of people with chronic LBP use complementary and alternative medicine (CAM), visit CAM practitioners, or both. Several herbal medicines have been purported for use in treating people with LBP. This is an update of a Cochrane Review fir...

The snowball Earth hypothesis predicts globally synchronous glaciations that persisted on a multimillion year time scale. Geochronological tests of this hypothesis have been limited by a dearth of reliable age constraints bracketing these events on multiple cratons. Here we present four new Re-Os geochronology age constraints on Sturtian (717–660 Ma) and Marinoan (635 Ma termination) glacial de...

BACKGROUND Launaea procumbens (Asteraceae) is used as a folk medicine to treat hepatic disorders in Pakistan. The effect of a chloroform extract of Launaea procumbens (LPCE) was evaluated against carbon-tetrachloride (CCl4)-induced liver damage in rats. METHODS To evaluate the hepatoprotective effects of LPCE, 36 male Sprague-Dawley rats were equally divided into six groups. Animals of group ...

Tribe Anthocercideae (Solanaceae) is an Australian endemic group comprising 31 species in seven genera. Recent phylogenetic work has placed the Anthocercideae sister to Nicotiana. Two chloroplast DNA regions, ndhF and trnL/ F, were analyzed and the phylogeny was used to test the tribe’s monophyly, discover relationships within the tribe, and make inferences on character evolution and biogeograp...

Exposure of macrophages to lipopolysaccharide (LPS) induces release of tumor necrosis factor(TNF), which is initially synthesized as a 26-kDa pro-TNFfollowed by proteolytic processing to a 17-kDa secreted form. In this study, justicidin A, an arylnaphthalide lignan isolated from Justicia procumbens, was found to inhibit LPS-stimulated TNFrelease from RAW 264.7 macrophages in a concentrationand ...