The synthesis of pharmaceutical products often involves the use of reactive reagents for the formation of intermediates and active pharmaceutical ingredient (API). Low-levels of reagents or byproducts may therefore be present in the final API as impurities. Such chemically reactive impurities may have unwanted toxicities such as genotoxicity and carcinogenicity, which have the potential impact ...

The objective of this study was to investigate the effect a dry headspace on thermal resistance bacteria in lipid oil and peanut butter. Our recent found Enterococcus faecium be extremely resistant heat thin layer when exposing environment. Thus, we hypothesized that or butter is contact with air during process may cause surface drying and, therefore, protect from inactivation. In research, tre...

Cultures of Penicillium expansum produce a musty, earthy odor. Geosmin [1,10-trans-dimethyl-trans(9)-decalol] was identified by gas chromatography-mass spectrometry from headspace samples of P. expansum cultures. Olfactory comparison of P. expansum cultures with a geosmin standard indicated geosmin is the primary component of the odor associated with P. expansum.

The one-bottle Oxoid Signal blood culture system altered to provide a more aerobic bottle headspace was reassessed in a comparative study versus the two-bottle BACTEC radiometric system in 5,426 blood cultures. The BACTEC system detected more microorganisms (P less than 0.02), particularly anaerobes (P less than 0.05) and fungi (P less than 0.05).

Two common bacteria, Streptococcus pyogenes and Pseudomonas aeruginosa, were differentiated based on their volatile metabolic waste products. The bacteria were cultured in a closed system and the headspace above the culture medium were collected, preconcentrated, and analyzed using a gas chromatography Fourier transform ion cyclotron resonance mass spectrometer (GC/FT-ICR MS).

A headspace-proton-transfer-reaction time-of-flight mass spectrometer (PTR-TOF/MS) system that combines PTR-TOF/MS with a dynamic and reactive flavor-release monitoring was constructed to measure the orthonasal aroma components in beer before after foaming. Some headspace of foaming real time, such as m/z 145.1150 173.1536, are thought be derived mainly from ethyl hexanoate octanoate, respectiv...

Abstract. Headspace analysis of CO2 frequently has been used to quantify the concentration in fresh water. According basic chemical theory, not considering equilibration carbonate system sample vials will result a systematic error. By analysing potential error for different types water and experimental conditions, we show that incurred by headspace is less than 5 % typical samples from boreal s...

Abstract Culture supernatants of Basfia succiniciproducens derived from the industrial production succinic acid exhibit an intense nutty, root vegetable‐like, buttery and sourish smell. By means headspace‐gas chromatography‐mass spectrometry‐olfactometry (HS‐GC‐MS‐O), 14 odour‐active compounds were perceived identified using two GC‐columns different polarity comparison retention indices mass sp...

a combined gas chromatography–mass spectrometry (gc–ms) with headspace solid-phase microextraction (hs-spme) method has been employed for the analysis of the flavor volatiles of some iranian rice cultivars (domsiah, deylamani, hashemi, shirodi and tarom). the samples were grown in different cities of mazandaran province. the sampling procedure and chromatographic conditions were same for all sa...

Ammonia emitted from manure can have detrimental effects on health, environmental quality, and fertilizer value. The objective of this study was to measure the potential for reduction in ammonia volatilization from swine (Sus scrofa domestica) manure by temperature control, stirring, addition of nitrogen binder (Mohave yucca, Yucca schidigera Roezl ex Ortgies) or urease inhibitor [N-(n-butyl) t...