In most modern societies, the relationship that many individuals have with food has fundamentally changed from previous generations. People have shifted away from viewing food as primarily sustenance, and rather now seek out foods based on pure palatability or specific nutrition. However, it is far from clear what optimal nutrition is for the general population or specific individuals. We previ...

OBJECTIVE To determine whether there is an increased amount of free radical-mediated damage in diseased vs healthy tissue from patients with chronic rhinosinusitis. DESIGN Pathophysiologic study. Samples of heathly and diseased tissue were taken from each patient. Lipid peroxides (LPOs) are a by-product of free radical-mediated damage; LPO levels and LPO/protein ratios were determined for eac...

A decrease in the almost fifty percent mortality rate from oral cancer is needed urgently. Improvements in early diagnosis and more effective preventive treatments could affect such a decrease. Towards this end, we undertook for the first time an in-depth mass spectrometry-based quantitative shotgun proteomics study of non-invasively collected oral brush biopsies. Proteins isolated from brush b...

In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined to develop bioartificial substitutes for organs and tissues, which can in turn be applied in regenerative medicine, pharmaceutical, diagnostic, and basic research to elucidate fundamental aspects of cell functions in vivo or to identify mechanisms involved in aging processes and disease onset and progressi...

introduction: full crown preparation may have adverse effects on pulp tissue. in this study, the effect of full-crown preparation on intact versus inflamed pulp tissue was studied. methods: fifteen healthy mature cats were randomly selected for this study. the study was performed on four canine teeth of each cat. cats were anesthetized and then radiographs were taken from the canine teeth. clas...

In this work, we present and analyze a mathematical model for tumor growth incorporating ECM erosion, interstitial flow, the effect of vascular flow nutrient transport. The is phase-field or diffused-interface type in which multiple phases cell species other constituents are separated by smooth evolving interfaces. involves mesoscale version Darcy’s law to capture mechanism tissue matrix. Model...

Radiation therapy is a widely used cancer treatment that utilizes high-energy radiation to target and destroy cells. However, challenges such as resistance exposure of healthy tissue the can limit its effectiveness. In this article, we explore various methods have been developed increase effectiveness in treatment. These include fractionation, image-guided (IGRT), radio sensitizers, hyper immun...