Local thermal enhancement in target tissue is of great interest in tumor hyperthermia. In this study, we proposed a brand-new thermal enhancement protocol for tumor hyperthermia using heat generated from thermogenesis evoked by capsaicin, which can safely deliver a totally localized heating to target tissue. A healthy male volunteer was recruited, whose partial areas of the dorsum of hand and p...

BACKGROUND Although clinical applications such as emergency medicine and prehospital care could benefit from a fast-mounting electroencephalography (EEG) recording system, the lack of specifically designed equipment restricts the use of EEG in these environments. METHODS This paper describes the design and testing of a six-channel emergency EEG (emEEG) system with a rapid preparation time int...

PURPOSE To investigate spatial distribution of iron accumulation in the globus pallidus (GP) in patients with Hallevorden-Spatz syndrome (HSS) using phase imaging. We compared sensitivity of a phase imaging technique to relaxation rate measurement methods (R1,R2,R2*) for iron quantification. MATERIALS AND METHODS R1, R2, and R2* were measured in GP structure of the brain of eight pantothenate...

BACKGROUND Neurofibromas represent proliferation of the connective tissue cells of peripheral nerves and deposition of collagenous extracellular matrix. There is evidence that the appearance and growth of neurofibromas may be associated with prior or ongoing mechanical trauma in patients with neurofibromatosis type 1 (NF1). OBJECTIVE To study the histologic characteristics of apparently healt...

CONTEXT The single-nucleotide polymorphism rs1344706 in the gene ZNF804a has been associated with schizophrenia and with quantitative phenotypic features, including brain structure volume and the core symptoms of schizophrenia. OBJECTIVE To evaluate associations of rs1344706 with brain structure and the core symptoms of schizophrenia. DESIGN Case-control analysis of covariance. SETTING Universi...

Acetanilide like phenylbutazone is paraoxidized by the liver endoplasmic reticulum as a primary biotransformation step. Both compounds were given at different times to each of 10 healthy volunteer subjects and the plasma disappearances measured. Correlation was shown between plasma clearance values of the two compounds (r = + 0.7067; P < 0.05).Eight patients with hypoplastic anaemia after pheny...

BACKGROUND Surveillance of infectious disease markers in the blood donor population is important in recognizing trends in prevalence and incidence of transfusion related infections in asymptomatic volunteer blood donors. SUBJECTS AND METHODS It was a cross sectional study. Samples were collected from volunteer blood donors and questionnaire was designed to collect the risk factors data. The p...

PURPOSE Electrocardiogram (ECG) triggering for cardiac magnetic resonance (CMR) may be influenced by electromagnetic interferences with increasing magnetic field strength. The aim of this study was to evaluate the performance of Doppler ultrasound (DUS) as an alternative trigger technique for CMR in comparison to ECG and pulse oximetry (POX) at 3T and using different sequence types. METHODS B...

Background 4D Phase-Contrast MRI ("4D Flow”) has become a choice modality for assessment of flow patterns in complex vasculatures, such as congenital heart diseases. For thoracic imaging, the technique relies on ECG-triggering and an imaging navigator to compensate for breathing motion [Markl-JMRI2007]. The acquisition of the navigator requires switching off the 4D flow acquisition, thus breaki...