background: radiation therapy  uses high-energy radiation to kill cancer cells. photoneutron contamination and induced radioactivity of high energy therapeutic photon beams are considered as the main source of occupational exposure to radiation therapists who works with linear accelerators operating above 10 mv. materials and methods: the gamma dose rates were measured after termination of diff...

introduction: despite potential benefits of cpoe (computerized physician order entry) systems, recent studies have cast some doubts on their role in reducing errors. cpoe systems with poorly designed interfaces have proven to cause dissatisfaction and introduce new kinds of errors in the ordering process. the main objective of this study is to identify problems related to a cpoe medication syst...

AIMS We aimed to document the drug management of patients at high cardiovascular risk in daily practice, with the special focus on lipid-lowering treatment. METHODS AND RESULTS In this prospective noninterventional study in 2387 outpatient centers throughout Germany, a total of 13,942 high-risk patients (mean age 65.7 years, 61.6% males) were treated with simvastatin 40 mg/day at entry as mon...

BACKGROUND Hypertension is assumed to be one of the mechanisms through which job strain (a combination of high work demands and low job control) increases coronary heart-disease risk. However, direct tests of this hypothesis are lacking. METHODS We examined whether hypertension mediated the association between job strain and incident coronary heart disease among 5630 men and 2456 women free o...

Abstract Background Statin therapy reduces rates of heart attacks and strokes improves survival in people at increased cardiovascular disease (CVD) risk. However, there is some uncertainty when to start how long persist with statin so as optimise benefits. Purpose To project the accrual benefit population groups by age initiation using a newly developed micro-simulation model. Methods Participa...

BACKGROUND We investigated the relationship between wavefront curvature and slowing of conduction both within and outside the diastolic pathway of circuits causing ventricular tachycardia (VT) in the infarcted human heart. METHODS AND RESULTS Propagation was determined around the reentrant circuits of 11 VT (cycle length, 348+/-75 ms) in 8 patients undergoing high-resolution noncontact mappin...

CONTEXT It is commonly suggested that more than 50% of patients with coronary heart disease (CHD) lack any of the conventional risk factors (cigarette smoking, diabetes, hyperlipidemia, and hypertension). This claim implies that other factors play a significant role in CHD and has led to considerable interest in nontraditional risk factors and genetic causes of CHD. OBJECTIVE To determine the...